node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0313 | SSO1879 | SSO0313 | SSO1879 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | 0.914 |
SSO0313 | TFB-1 | SSO0313 | SSO0446 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | Transcription initiation factor IIB (TFIIB) homolog (TFB-1); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.916 |
SSO0313 | rad2 | SSO0313 | SSO0179 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | DNA repair endo/exonuclease FEN-1 (RAD2) (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base exci [...] | 0.953 |
SSO0313 | rpoD | SSO0313 | SSO0071 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.967 |
SSO0313 | rpoH | SSO0313 | SSO5468 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.965 |
SSO0313 | rpoK | SSO0313 | SSO6768 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | DNA-directed RNA polymerase subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.971 |
SSO0313 | rpoN | SSO0313 | SSO5140 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.963 |
SSO0313 | tfE | SSO0313 | SSO0266 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.982 |
SSO0313 | tfIID | SSO0313 | SSO0951 | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | TATA box binding protein, hypothetical (tfIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). | 0.970 |
SSO0475 | SSO1879 | SSO0475 | SSO1879 | Conserved hypothetical protein; Some homology to B.burgdorferi predicted coding region BB0212. | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | 0.902 |
SSO1879 | SSO0313 | SSO1879 | SSO0313 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA helicase; Similar to CHL1 (S.cerevisiae). Belongs to the RAD3/XPD subfamily of helicases; Helicases, Helicases. | 0.914 |
SSO1879 | SSO0475 | SSO1879 | SSO0475 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | Conserved hypothetical protein; Some homology to B.burgdorferi predicted coding region BB0212. | 0.902 |
SSO1879 | TFB-1 | SSO1879 | SSO0446 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | Transcription initiation factor IIB (TFIIB) homolog (TFB-1); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.888 |
SSO1879 | rad2 | SSO1879 | SSO0179 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA repair endo/exonuclease FEN-1 (RAD2) (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base exci [...] | 0.907 |
SSO1879 | rpoD | SSO1879 | SSO0071 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.885 |
SSO1879 | rpoH | SSO1879 | SSO5468 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA-directed RNA polymerase, subunit H (rpoH); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.896 |
SSO1879 | rpoK | SSO1879 | SSO6768 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA-directed RNA polymerase subunit K (rpoK); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. | 0.885 |
SSO1879 | rpoN | SSO1879 | SSO5140 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | DNA-directed RNA polymerase, subunit N (rpoN); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.882 |
SSO1879 | tfE | SSO1879 | SSO0266 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.913 |
SSO1879 | tfIID | SSO1879 | SSO0951 | ATP-dependent helicase, putative; Contains a DNA/RNA helicase domain (DEAD/DEAH box); Helicases. | TATA box binding protein, hypothetical (tfIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity). | 0.899 |