STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhA-4NAD specific glutamate dehydrogenase (gdhA-4); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase (NADPH) subunit alpha (gltB); Amino Acid Biosynthesis, Glutamate.
  
 
 0.867
idh
Isocitrate dehydrogenase, probable (idh); Energy Metabolism, Tri-Carboxylic Acid Cycle.
  
 0.708
cobB
Transcriptional regulatory protein, Sir2 protein homolog; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
  
 0.673
SSO0683
Conserved hypothetical protein.
  
 
 0.638
NuoB
NADH dehydrogenase subunit B (NuoB); Energy Metabolism, Electron transport; Belongs to the complex I 20 kDa subunit family.
   
  
 0.632
SSO8549
Hypothetical protein.
      
 0.612
SSO2815
2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.
  
  
 0.591
SSO3216
Gamma-glutamyltranspeptidase, hypothetical; Cofactor Biosynthesis, Glutathione.
  
  
 0.590
purF-1
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
     
 0.548
pdhA-1
Pyruvate dehydrogenase, alpha subunit (lipoamide). (pdhA-1); Strong similarity to acetoin:DCPIP oxidoreductase-alpha (acoA) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
  
  
 0.547
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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