node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO2231 | trxA-2 | SSO2231 | SSO2232 | Hypothetical protein. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.852 |
bcp-2 | msr | SSO2121 | SSO1503 | Peroxiredoxin, bacterioferritin comigratory protein homolog (bcp-2); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Peptide methionine sulfoxide reductase (msr); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.578 |
bcp-2 | trxA-2 | SSO2121 | SSO2232 | Peroxiredoxin, bacterioferritin comigratory protein homolog (bcp-2); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.911 |
bcp-2 | trxB-3 | SSO2121 | SSO2416 | Peroxiredoxin, bacterioferritin comigratory protein homolog (bcp-2); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Thioredoxin reductase (trxB-3); Pyrimidines. | 0.947 |
merA | pdhD-2 | SSO2689 | SSO1524 | Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.441 |
merA | pdhD-3 | SSO2689 | SSO1565 | Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.447 |
merA | pdhD-4 | SSO2689 | SSO2559 | Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.421 |
merA | trxA-2 | SSO2689 | SSO2232 | Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.734 |
msr | bcp-2 | SSO1503 | SSO2121 | Peptide methionine sulfoxide reductase (msr); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Peroxiredoxin, bacterioferritin comigratory protein homolog (bcp-2); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.578 |
msr | trxA-2 | SSO1503 | SSO2232 | Peptide methionine sulfoxide reductase (msr); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.896 |
nrd | trxA-2 | SSO0929 | SSO2232 | Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.768 |
pdhD-1 | pdhD-2 | SSO1123 | SSO1524 | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.922 |
pdhD-1 | pdhD-3 | SSO1123 | SSO1565 | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.920 |
pdhD-1 | pdhD-4 | SSO1123 | SSO2559 | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.918 |
pdhD-1 | trxA-2 | SSO1123 | SSO2232 | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.734 |
pdhD-2 | merA | SSO1524 | SSO2689 | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.441 |
pdhD-2 | pdhD-1 | SSO1524 | SSO1123 | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.922 |
pdhD-2 | pdhD-3 | SSO1524 | SSO1565 | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.925 |
pdhD-2 | pdhD-4 | SSO1524 | SSO2559 | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.902 |
pdhD-2 | trxA-2 | SSO1524 | SSO2232 | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Thioredoxin (trxA-2); Energy Metabolism, Electron transport. | 0.734 |