STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSO2281Conserved hypothetical protein; Involved in the synthesis of UDP-N-acetylgalactosamine (UDP- GalNAc). Catalyzes the conversion of glucosamine-6-phosphate (GlcN-6-P) to galactosamine-6-phosphate (GalN-6-P). Belongs to the PGI/PMI family. (296 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.999
pgk
Phosphoglycerate kinase; Energy Metabolism, Gluconeogenesis.
 
 
 0.998
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.994
gap
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (gap); Can use both NAD and NADP as cofactors, but exhibits a marked preference for NADP; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.992
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
  
  
 0.981
pyK
Pyruvate kinase (pyK); Energy Metabolism, Glycolysis; Belongs to the pyruvate kinase family.
  
 
 0.976
pmM
Phosphomannomutase (pmM); Cell Envelope, Surface polysaccharides and lipopolysaccharides; Belongs to the phosphohexose mutase family.
  
 
 0.970
hpS-1
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hpS-1); Energy Metabolism.
    
 0.950
apgM
Phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
 
 0.938
tkt-1
Transketolase, N-terminal section (tkt-1); Energy Metabolism, Sugar metabolism.
 
  
 0.932
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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