STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adh-6Alcohol dehydrogenase (Zn containing) (adh-6); Energy Metabolism. (338 aa)    
Predicted Functional Partners:
SSO2336
Hypothetical protein.
     
 0.772
SSO2337
Hypothetical protein.
       0.675
acd-like2
Acyl-CoA dehydrogenase related protein (acd-like2); Lipid metabolism.
  
 
 0.661
fdhF-2
Formate dehydrogenase Alpha subunit (fdhF-2); Energy Metabolism.
  
  
 0.604
leuA-2
2-isopropylmalate synthase (leuA-2); Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
   
 
 0.591
dhg-3
Glucose 1-dehydrogenase (dhg-3); Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
 
  
 0.588
SSO1906
Amino acid transporter related protein; Transport.
     
 0.579
SSO2043
Amino acid transporter related protein; Transport.
     
 0.579
SSO0572
Conserved hypothetical protein; Some homology to twitching mobility (pilt) related protein.
      
 0.545
adh-7
Alcohol dehydrogenase (Zn containing) (adh-7); Energy Metabolism.
 
  
0.503
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.