STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpT-1Purine phosphoribosyltransferase (gpT-1); Purines. (210 aa)    
Predicted Functional Partners:
mtaP
5'-methylthioadenosine phosphorylase (mtaP); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
  
 0.900
gnptA
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (gnptA); Cell Envelope, Surface polysaccharides and lipopolysaccharides.
     
 0.843
gdS-2
Geranylgeranyl pyrophosphate synthetase, putative (gdS-2); Catalyzes consecutive E-type condensation of two isopentenyl pyrophosphate (IPP) molecules with an allylic substrate such as geranylgeranyl diphosphate (GGPP), farnesyl diphosphate (FPP) or geranyl diphosphate (GPP) to yield the medium-chain product trans-C30- hexaprenyl pyrophosphate (HexPP). GGPP is the physiological substrate.
 
    0.634
SSO0049
Conserved hypothetical protein.
      
 0.612
SSO2344
Hypothetical protein; Similarity with fungal farnesyl-pyrophosphate synthetase.
       0.593
rimK-3
Translation, Protein modification.
       0.552
deoD
Purine nucleoside phosporylase (deoD); Purines.
    
  0.528
SSO0251
Hypothetical protein.
   
    0.445
rtcA
RNA 3' terminal phosphate cyclase (RNA 3' phosphate cyclase) (RNA cyclase) (rtcA); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
   
    0.426
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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