STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhCSuccinate dehydrogenase subunit C (sdhC); Iron-sulfur subunit C; also hit with htrB2 subunit of heterodisulfide reductase; Energy Metabolism, Electron transport. (293 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase subunit A (sdhA); Flavoprotein subunit; Energy Metabolism, Electron transport.
 
 
 0.999
sdhB
Succinate dehydrogenase subunit B (sdhB); Iron-sulfur subunit B; Energy Metabolism, Electron transport.
 
 
 0.998
sdhD
Succinate dehydrogenase subunit D (sdhD); Subunit D; Energy Metabolism, Electron transport.
    
 0.986
hdrA
Heterodisulfide reductase, subunit A (hdrA); Energy Metabolism.
 
 0.983
sucD
Succinyl-CoA synthetase, alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.910
fumC
Fumarate hydratase classe II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
    
  0.907
maiA
Maleate cis-trans isomerase, probable (maiA); Cofactor Biosynthesis.
     
  0.900
hdrC-2
Heterodisulfide reductase subunit C (hdrC-2); Energy Metabolism.
 
 
 0.825
aspB-2
Aspartate aminotransferase (aspB-2); Amino Acid Biosynthesis, Aspartate.
  
 
 0.814
argH
Argininosuccinate lyase (argH); Amino Acid Biosynthesis, Glutamate.
    
  0.800
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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