node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0039 | SSO2171 | SSO0039 | SSO2171 | Conserved hypothetical protein. | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.915 |
SSO0039 | thi4 | SSO0039 | SSO0436 | Conserved hypothetical protein. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.458 |
SSO0039 | thiD-2 | SSO0039 | SSO2393 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.920 |
SSO0039 | thiL | SSO0039 | SSO0237 | Conserved hypothetical protein. | Thiamine monophosphate kinase, putative (thiL); Cofactor Biosynthesis, Thiamine. | 0.929 |
SSO2171 | SSO0039 | SSO2171 | SSO0039 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Conserved hypothetical protein. | 0.915 |
SSO2171 | thiD-2 | SSO2171 | SSO2393 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.907 |
SSO2171 | thiL | SSO2171 | SSO0237 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Thiamine monophosphate kinase, putative (thiL); Cofactor Biosynthesis, Thiamine. | 0.900 |
SSO2391 | moaE | SSO2391 | SSO2394 | Conserved hypothetical protein. | Cofactor Biosynthesis, Molybdopterin. | 0.920 |
SSO2391 | thiD-2 | SSO2391 | SSO2393 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.822 |
moaE | SSO2391 | SSO2394 | SSO2391 | Cofactor Biosynthesis, Molybdopterin. | Conserved hypothetical protein. | 0.920 |
moaE | thiD-2 | SSO2394 | SSO2393 | Cofactor Biosynthesis, Molybdopterin. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.932 |
tenA-1 | tenA-2 | SSO2206 | SSO2598 | Transcriptional activator (tenA-1); Similarity with putative transcription activator; Transcription, RNA polymerase and transcription factors. | Transcriptional activator (tenA-2); Transcription, RNA polymerase and transcription factors. | 0.918 |
tenA-1 | thiC-1 | SSO2206 | SSO1324 | Transcriptional activator (tenA-1); Similarity with putative transcription activator; Transcription, RNA polymerase and transcription factors. | Thiamine biosynthesis protein (thiC-1); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.548 |
tenA-1 | thiC-2 | SSO2206 | SSO1941 | Transcriptional activator (tenA-1); Similarity with putative transcription activator; Transcription, RNA polymerase and transcription factors. | Thiamine biosynthesis protein (thiC-2); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.548 |
tenA-1 | thiD-2 | SSO2206 | SSO2393 | Transcriptional activator (tenA-1); Similarity with putative transcription activator; Transcription, RNA polymerase and transcription factors. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.986 |
tenA-2 | tenA-1 | SSO2598 | SSO2206 | Transcriptional activator (tenA-2); Transcription, RNA polymerase and transcription factors. | Transcriptional activator (tenA-1); Similarity with putative transcription activator; Transcription, RNA polymerase and transcription factors. | 0.918 |
tenA-2 | thiC-1 | SSO2598 | SSO1324 | Transcriptional activator (tenA-2); Transcription, RNA polymerase and transcription factors. | Thiamine biosynthesis protein (thiC-1); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.548 |
tenA-2 | thiC-2 | SSO2598 | SSO1941 | Transcriptional activator (tenA-2); Transcription, RNA polymerase and transcription factors. | Thiamine biosynthesis protein (thiC-2); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.548 |
tenA-2 | thiD-2 | SSO2598 | SSO2393 | Transcriptional activator (tenA-2); Transcription, RNA polymerase and transcription factors. | Phosphomethylpyrimidine kinase (thiD-2); Cofactor Biosynthesis, Thiamine. | 0.998 |
thi4 | SSO0039 | SSO0436 | SSO0039 | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | Conserved hypothetical protein. | 0.458 |