STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSO2464Biotin carboxyl carrier protein of propionyl-CoA carboxylase beta subunit; Lipid metabolism. (186 aa)    
Predicted Functional Partners:
accC
Biotin carboxylase a subunit of propionyl-CoA carboxylase (accC); Lipid metabolism.
 
 
 0.999
bioR
Biotin--(acetyl-CoA carboxylase) synthetase (bioR); Cofactor Biosynthesis, Biotin.
 
 
 
 0.945
ppcB
Propionyl-CoA carboxylase beta subunit (ppcB); Lipid metabolism.
 
  
 0.936
pdhA-2
Pyruvate dehydrogenase, alpha subunit (lipoamide). (pdhA-2); Strong similarity to acetoin:DCPIP oxidoreductase-alpha (acoA) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
    
 0.642
pdhD-3
Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.601
pdhB-2
Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
    
 0.591
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.564
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor. Is also able to phosphorylate dUMP, although much less efficiently.
 
    0.551
eiF5A
Initiation factor 5A, hypothetical (eiF5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
  
 0.531
rpl1AB
LSU ribosomal protein L1AB (rpl1AB); Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA (Probable).
   
  
 0.513
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.