STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSO2586Conserved hypothetical protein; Belongs To The MMGE / PRPD family. Similar to APE2147. (435 aa)    
Predicted Functional Partners:
prpB
Carboxyphosphonoenolpyruvate phosphonomutase (CPEP Phosphonomutase), putative (prpB); Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
  
 0.995
gltA
Citrate synthase; Energy Metabolism; Belongs to the citrate synthase family.
 
  
 0.987
sqdB-2
L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
  
 0.808
ppcB
Propionyl-CoA carboxylase beta subunit (ppcB); Lipid metabolism.
  
    0.754
SSO2588
Hypothetical protein; Putative inosine 5' monophosphate dehydrogenase (guaB).
       0.693
sdhB
Succinate dehydrogenase subunit B (sdhB); Iron-sulfur subunit B; Energy Metabolism, Electron transport.
 
  
 0.650
citE
Citryl-CoA lyase beta subunit homolog (citE); Energy Metabolism.
  
  
 0.643
AcnA
Aconitate hydratase; Energy Metabolism, Tri-Carboxylic Acid Cycle.
  
  
 0.597
SSO2590
Conserved hypothetical protein.
       0.592
metB
O-succinylhomoserine (thiol)-lyase (cystathionine gamma-synthase) (metB); Amino Acid Biosynthesis.
  
    0.424
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.