STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thsCThermosome subunit gamma; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. (539 aa)    
Predicted Functional Partners:
thsA
Thermosome subunit alpha; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
  
 
 
0.887
tfIID
TATA box binding protein, hypothetical (tfIID); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
 
 
 0.831
pfdA
Conserved hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
   
 
 0.777
eiF5A
Initiation factor 5A, hypothetical (eiF5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.751
SSO1046
Hypothetical ATP/GTP binding protein.
 
 0.751
rpl4AE
LSU ribosomal protein L4AE (rpl4AE); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 0.748
psmA
Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 
 0.747
eiF1A
Translation initiation factor 1A homolog (EIF 1A) (eif1A) (eiF1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
 
 
 0.728
infB
Translation initiation factor IF2 homolog (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
 
 0.720
pfdB
Hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
    
 
 0.710
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.