STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thsCThermosome subunit gamma; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity (539 aa)    
Predicted Functional Partners:
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation
  
 
 0.719
rps17AB
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
 
  
 0.705
rpl4AE
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
 
 
 0.700
eiF5A
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond
 
 
 0.699
SSO2998
Uncharacterized protein; Probably belongs to mandelate racemase / muconate lactonizing enzyme family
       0.697
rpoA1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
 
 
 0.696
rpS13E
30S ribosomal protein S15; Close hits to several plant species' 40S ribosomal protein; Translation, Ribosomal Proteins
 
  
 0.691
rpoA2
DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
 
 
 0.687
rpl10E
Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uL16 family
 
 
 0.687
eiF1A
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity)
 
  
 0.672
Your Current Organism:
Sulfolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Sulfolobus solfataricus, Sulfolobus solfataricus P2, Sulfolobus solfataricus str. P2, Sulfolobus solfataricus strain P2
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