node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ST0202 | ST2410 | STK_02020 | STK_24100 | Hypothetical protein; N-term changed (-123). | Hypothetical protein. | 0.726 |
ST0202 | ilvC | STK_02020 | STK_14450 | Hypothetical protein; N-term changed (-123). | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.943 |
ST0202 | ilvD | STK_02020 | STK_21720 | Hypothetical protein; N-term changed (-123). | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.884 |
ST0202 | leuB | STK_02020 | STK_04330 | Hypothetical protein; N-term changed (-123). | Putative 3-isopropylmalate dehydrogenase/homoisocitrate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.684 |
ST0202 | lysT/leuD | STK_02020 | STK_06000 | Hypothetical protein; N-term changed (-123). | Homoaconitase/3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.700 |
ST0202 | lysU/leuC | STK_02020 | STK_05990 | Hypothetical protein; N-term changed (-123). | Homoaconitase/3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.679 |
ST0202 | tdcB | STK_02020 | STK_02950 | Hypothetical protein; N-term changed (-123). | Threonine dehydratase. | 0.610 |
ST0752 | ilvC | STK_07520 | STK_14450 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.940 |
ST0752 | ilvD | STK_07520 | STK_21720 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.878 |
ST0752 | leuB | STK_07520 | STK_04330 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Putative 3-isopropylmalate dehydrogenase/homoisocitrate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.656 |
ST0752 | lysT/leuD | STK_07520 | STK_06000 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Homoaconitase/3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.701 |
ST0752 | lysU/leuC | STK_07520 | STK_05990 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Homoaconitase/3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.681 |
ST0752 | tdcB | STK_07520 | STK_02950 | Putative acetolactate synthase; Belongs to the TPP enzyme family. | Threonine dehydratase. | 0.608 |
ST1446 | ilvB | STK_14460 | STK_14470 | Hypothetical protein; N-terminus of this ORF was identified by Edman sequencing. | Acetolactate synthase. | 0.834 |
ST1446 | ilvC | STK_14460 | STK_14450 | Hypothetical protein; N-terminus of this ORF was identified by Edman sequencing. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.854 |
ST2410 | ST0202 | STK_24100 | STK_02020 | Hypothetical protein. | Hypothetical protein; N-term changed (-123). | 0.726 |
ST2410 | ilvB | STK_24100 | STK_14470 | Hypothetical protein. | Acetolactate synthase. | 0.927 |
ST2410 | ilvC | STK_24100 | STK_14450 | Hypothetical protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.985 |
ST2410 | ilvD | STK_24100 | STK_21720 | Hypothetical protein. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.849 |
ST2410 | leuB | STK_24100 | STK_04330 | Hypothetical protein. | Putative 3-isopropylmalate dehydrogenase/homoisocitrate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.962 |