STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (308 aa)    
Predicted Functional Partners:
gltA-2
Citrate synthase.
  
 0.996
gltA
Citrate synthase.
  
 0.993
fumC
Fumarate hydratase; N-term changed (-3); protein synonym:fumarase C.
 
 0.992
idh
Isocitrate dehydrogenase.
  
 
 0.982
aspC
Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 0.974
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
    
 0.953
ST2090
2-hydroxyacid dehydrogenase.
    
 0.947
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.945
ST0114
Malate dehydrogenase; Protein synonym:NADP(+)-dependent malic enzyme.
  
 0.944
ST0278
Malate dehydrogenase; N-term changed (-51); protein synonym:NADP(+)-dependent malic enzyme.
  
 0.944
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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