STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiLCobalt-factor II C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. (222 aa)    
Predicted Functional Partners:
cbiH
precorrin-3B C(17)-methyltransferase.
  
 0.999
cbiF
Precorrin-4 C(11)-methyltransferase; N-term changed (+159); Belongs to the precorrin methyltransferase family.
 
  
0.998
cbiC
precorrin-8X methylmutase.
 
  
 0.997
cbiT
Probable cobalt-precorrin-6Y C(15)-methyltransferase; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
  
 0.995
cbiD
Putative cobalt-precorrin 6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.993
cbiG
Cobalamin biosynthesis protein CbiG; N-term changed (+153).
 
  
 0.991
cbiP
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.981
cbiXS
Sirohydrochlorin cobaltochelatase CbiXS; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Belongs to the CbiX family. CbiXS subfamily.
 
  
 0.973
ST0211
Precorrin-2 dehydrogenase; N-term changed (-42).
    
 0.965
ST1825
Putative cobalamin biosynthesis protein.
 
  
0.949
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.