STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
endARNA splicing endonuclease alpha subunit; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (180 aa)    
Predicted Functional Partners:
ST0357
Hypothetical protein.
       0.854
STK_03225
RNA splicing endonuclease beta subunit; Protein synonym:RNA intron endonuclease.
    
 
 0.834
glyS
glycyl-tRNA synthetase; Protein synonym:glycine--tRNA ligase.
  
    0.817
ST0355
Hypothetical protein; N-term changed (-6).
       0.807
dnaG
Exosome subunit DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.802
ST0356
Hypothetical protein.
       0.801
hom
Homoserine dehydrogenase; N-term changed (-24).
      
 0.762
ST0359
Hypothetical protein.
       0.698
ST0463
Hypothetical protein.
  
 
 0.688
trpS
tryptophanyl-tRNA synthetase; N-term changed (-75); protein synonym:tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   
 0.638
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.