STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ST24332-oxoacid--ferredoxin oxidoreductase beta subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives. (304 aa)    
Predicted Functional Partners:
ST2300
2-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives.
 
 0.999
ST2435
2-oxoacid--ferredoxin oxidoreductase alpha subunit; Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2- oxobutyrate to form their CoA derivatives.
 
 0.999
ST1788
2-oxoacid--ferredoxin oxidoreductase alpha subunit.
 
 0.965
ST1531
2-oxoacid--ferredoxin oxidoreductase gamma subunit.
  
 0.963
STK_17887
2-oxoacid--ferredoxin oxidoreductase gamma subunit; N-term changed (+273).
  
 0.963
ST1532
2-oxoacid--ferredoxin oxidoreductase alpha subunit.
  
 0.960
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.931
sucC
succinyl-CoA synthetase beta subunit; N-term changed (+195); N-terminus of this ORF was identified by Edman sequencing; protein synonym:succinate---CoA ligase.
  
 
 0.931
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.931
gltA
Citrate synthase.
  
 
 0.921
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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