node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GuaA | PurB | TTE0583 | TTE1367 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.891 |
GuaA | PurC | TTE0583 | TTE0588 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Best Blastp hit = gi|10173240|dbj|BAB04345.1| (AP001509) phosphoribosylaminoimidazole succinocarboxamide synthetase [Bacillus halodurans], score 266, E-value 2.00E-70; Belongs to the SAICAR synthetase family. | 0.799 |
GuaA | PurD | TTE0583 | TTE0593 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | 0.953 |
GuaA | PurE | TTE0583 | TTE0585 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.858 |
GuaA | PurF | TTE0583 | TTE0812 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.864 |
GuaA | PurH | TTE0583 | TTE0592 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Best Blastp hit = gi|10173247|dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans], score 611, E-value 1.00E-174. | 0.930 |
GuaA | PurL | TTE0583 | TTE0810 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interac [...] | 0.846 |
GuaA | PurL2 | TTE0583 | TTE0811 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] | 0.948 |
GuaA | PurM | TTE0583 | TTE0590 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazol (AIR) synthetase; Best Blastp hit = gi|11272453|pir||E81104 phosphoribosylformylglycinamidine cyclo-ligase NMB1252 [imported] - Neisseria meningitidis (group B strain MD58) gi|7226492|gb|AAF41632.1| (AE002473) phosphoribosylformylglycinamidine cyclo-ligase [Neisseria meningitidis MC58], score 375, E-value 1.00E-103. | 0.817 |
GuaA | PurN | TTE0583 | TTE0591 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Folate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.797 |
PurB | GuaA | TTE1367 | TTE0583 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.891 |
PurB | PurC | TTE1367 | TTE0588 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Best Blastp hit = gi|10173240|dbj|BAB04345.1| (AP001509) phosphoribosylaminoimidazole succinocarboxamide synthetase [Bacillus halodurans], score 266, E-value 2.00E-70; Belongs to the SAICAR synthetase family. | 0.988 |
PurB | PurD | TTE1367 | TTE0593 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | 0.961 |
PurB | PurE | TTE1367 | TTE0585 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.945 |
PurB | PurF | TTE1367 | TTE0812 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.962 |
PurB | PurH | TTE1367 | TTE0592 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Best Blastp hit = gi|10173247|dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans], score 611, E-value 1.00E-174. | 0.995 |
PurB | PurL | TTE1367 | TTE0810 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interac [...] | 0.925 |
PurB | PurL2 | TTE1367 | TTE0811 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] | 0.941 |
PurB | PurM | TTE1367 | TTE0590 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazol (AIR) synthetase; Best Blastp hit = gi|11272453|pir||E81104 phosphoribosylformylglycinamidine cyclo-ligase NMB1252 [imported] - Neisseria meningitidis (group B strain MD58) gi|7226492|gb|AAF41632.1| (AE002473) phosphoribosylformylglycinamidine cyclo-ligase [Neisseria meningitidis MC58], score 375, E-value 1.00E-103. | 0.947 |
PurB | PurN | TTE1367 | TTE0591 | Adenylosuccinate lyase; Best Blastp hit = gi|3983439|gb|AAC83935.1| (AF106656) adenylosuccinate lyase [Homo sapiens], score 469, E-value 1.00E-131; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Folate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.933 |