STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GatAAsp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (488 aa)    
Predicted Functional Partners:
GatC
Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
 
 0.999
GatB
Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
 0.999
GlnS2
Glutamyl- and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.980
Dur1
Allophanate hydrolase subunit 2; Best Blastp hit = gi|10174436|dbj|BAB05537.1| (AP001513) BH1818; unknown conserved protein (divided) [Bacillus halodurans], score 215, E-value 6.00E-55.
    
 0.934
AspS
Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
 
 
 0.891
Lig
NAD-dependent DNA ligase (contains BRCT domain type II); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
    0.857
UvrD
Superfamily I DNA and RNA helicases; Best Blastp hit = gi|10173262|dbj|BAB04367.1| (AP001509) ATP-dependent DNA helicase [Bacillus halodurans], score 688, E-value 0.
  
    0.847
GlnS
Glutamyl- and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 
 0.815
TTE0183
Conserved hypothetical protein; Best Blastp hit = gi|13700162|dbj|BAB41461.1| (AP003129) ORFID:SA0238; probable PTS galactitol-specific enzyme IIC component [Staphylococcus aureus] gi|13873580|dbj|BAB44397.1| (AP003358) hypothetical protein [Staphylococcus aureus], score 382, E-value 1.00E-105.
   
    0.797
FruK
Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Best Blastp hit = gi|11259262|pir||C82450 1-phosphofructokinase VCA0517 [imported] - Vibrio cholerae (group O1 strain N16961) gi|9657922|gb|AAF96420.1| (AE004382) 1-phosphofructokinase [Vibrio cholerae], score 169, E-value 3.00E-41; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
   
  
 0.794
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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