Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GuaA | GuaB | TTE0583 | TTE0582 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| GuaA | Hpt | TTE0583 | TTE2394 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.975 |
| GuaA | Ndk | TTE0583 | TTE0747 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.717 |
| GuaA | Rph | TTE0583 | TTE0618 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.427 |
| GuaA | SurE | TTE0583 | TTE1338 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Survival protein, predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.974 |
| GuaA | TTE0620 | TTE0583 | TTE0620 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.978 |
| GuaA | UshA | TTE0583 | TTE0343 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 5-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Best Blastp hit = gi|7481086|pir||T35760 probable nucleotidase - Streptomyces coelicolor gi|5689908|emb|CAB52071.1| (AL109732) putative nucleotidase [Streptomyces coelicolor A3(2)], score 325, E-value 3.00E-87. | 0.946 |
| GuaB | GuaA | TTE0582 | TTE0583 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| GuaB | Hpt | TTE0582 | TTE2394 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.974 |
| GuaB | Ndk | TTE0582 | TTE0747 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.728 |
| GuaB | Rph | TTE0582 | TTE0618 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.413 |
| GuaB | SurE | TTE0582 | TTE1338 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Survival protein, predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.973 |
| GuaB | TTE0620 | TTE0582 | TTE0620 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.954 |
| GuaB | UshA | TTE0582 | TTE0343 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 5-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Best Blastp hit = gi|7481086|pir||T35760 probable nucleotidase - Streptomyces coelicolor gi|5689908|emb|CAB52071.1| (AL109732) putative nucleotidase [Streptomyces coelicolor A3(2)], score 325, E-value 3.00E-87. | 0.945 |
| Hpt | GuaA | TTE2394 | TTE0583 | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.975 |
| Hpt | GuaB | TTE2394 | TTE0582 | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.974 |
| Hpt | SurE | TTE2394 | TTE1338 | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Survival protein, predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| Hpt | TTE0620 | TTE2394 | TTE0620 | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.910 |
| Hpt | UshA | TTE2394 | TTE0343 | Best Blastp hit = gi|10172696|dbj|BAB03803.1| (AP001507) hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans], score 189, E-value 2.00E-47; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 5-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Best Blastp hit = gi|7481086|pir||T35760 probable nucleotidase - Streptomyces coelicolor gi|5689908|emb|CAB52071.1| (AL109732) putative nucleotidase [Streptomyces coelicolor A3(2)], score 325, E-value 3.00E-87. | 0.907 |
| MurI | MurI2 | TTE0209 | TTE0595 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.903 |
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