node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CarA | PurD | TTE0815 | TTE0593 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | 0.617 |
CarA | PurE | TTE0815 | TTE0585 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.579 |
CarA | PurF | TTE0815 | TTE0812 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.961 |
CarA | PurH | TTE0815 | TTE0592 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Best Blastp hit = gi|10173247|dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans], score 611, E-value 1.00E-174. | 0.624 |
CarA | PurL | TTE0815 | TTE0810 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interac [...] | 0.948 |
CarA | PurL2 | TTE0815 | TTE0811 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] | 0.560 |
CarA | PurM | TTE0815 | TTE0590 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Phosphoribosylaminoimidazol (AIR) synthetase; Best Blastp hit = gi|11272453|pir||E81104 phosphoribosylformylglycinamidine cyclo-ligase NMB1252 [imported] - Neisseria meningitidis (group B strain MD58) gi|7226492|gb|AAF41632.1| (AE002473) phosphoribosylformylglycinamidine cyclo-ligase [Neisseria meningitidis MC58], score 375, E-value 1.00E-103. | 0.625 |
CarA | TTE0808 | TTE0815 | TTE0808 | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | Conserved hypothetical protein; Best Blastp hit = gi|131631|sp|P12046|PUR7_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (SAICAR SYNTHETASE) (VEGETATIVE PROTEIN 286A) (VEG286A) gi|68623|pir||CEBSSC phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) - Bacillus subtilis gi|143367|gb|AAA22677.1| (J02732) phosphoribosyl aminoidazole succinocarboxamide synthetase (PUR-C; gtg start codon) [Bacillus subtilis] gi|2632959|emb|CAB12465.1| (Z99107) phosphoribosylaminoimidazole succinocarboxamide synthetase [Bacillus subtilis], score 67, E-value 3.00E-11. | 0.457 |
PurD | CarA | TTE0593 | TTE0815 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | 0.617 |
PurD | PurE | TTE0593 | TTE0585 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
PurD | PurF | TTE0593 | TTE0812 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
PurD | PurH | TTE0593 | TTE0592 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Best Blastp hit = gi|10173247|dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans], score 611, E-value 1.00E-174. | 0.997 |
PurD | PurL | TTE0593 | TTE0810 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interac [...] | 0.995 |
PurD | PurL2 | TTE0593 | TTE0811 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...] | 0.984 |
PurD | PurM | TTE0593 | TTE0590 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Phosphoribosylaminoimidazol (AIR) synthetase; Best Blastp hit = gi|11272453|pir||E81104 phosphoribosylformylglycinamidine cyclo-ligase NMB1252 [imported] - Neisseria meningitidis (group B strain MD58) gi|7226492|gb|AAF41632.1| (AE002473) phosphoribosylformylglycinamidine cyclo-ligase [Neisseria meningitidis MC58], score 375, E-value 1.00E-103. | 0.999 |
PurD | PurN | TTE0593 | TTE0591 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Folate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
PurD | PurS | TTE0593 | TTE0809 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and i [...] | 0.949 |
PurD | TTE0808 | TTE0593 | TTE0808 | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | Conserved hypothetical protein; Best Blastp hit = gi|131631|sp|P12046|PUR7_BACSU PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (SAICAR SYNTHETASE) (VEGETATIVE PROTEIN 286A) (VEG286A) gi|68623|pir||CEBSSC phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) - Bacillus subtilis gi|143367|gb|AAA22677.1| (J02732) phosphoribosyl aminoidazole succinocarboxamide synthetase (PUR-C; gtg start codon) [Bacillus subtilis] gi|2632959|emb|CAB12465.1| (Z99107) phosphoribosylaminoimidazole succinocarboxamide synthetase [Bacillus subtilis], score 67, E-value 3.00E-11. | 0.911 |
PurE | CarA | TTE0585 | TTE0815 | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Carbamoylphosphate synthase small subunit; Best Blastp hit = gi|1705597|sp|P52557|CARA_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, SMALL CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE GLUTAMINE CHAIN)' gi|2126769|pir||I40168 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312442|emb|CAA51738.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 381, E-value 1.00E-105; Belongs to the CarA family. | 0.579 |
PurE | PurD | TTE0585 | TTE0593 | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | Phosphoribosylamine-glycine ligase; Best Blastp hit = gi|10173248|dbj|BAB04353.1| (AP001509) phosphoribosylglycinamide synthetase [Bacillus halodurans], score 408, E-value 1.00E-113. | 0.999 |