node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OraA | PolA | TTE1373 | TTE0874 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.757 |
OraA | RecJ | TTE1373 | TTE1191 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | Best Blastp hit = gi|7475820|pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis], score 390, E-value 1.00E-107. | 0.552 |
OraA | RuvA | TTE1373 | TTE1179 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | Holliday junction resolvasome DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.685 |
OraA | RuvB | TTE1373 | TTE1180 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.617 |
OraA | RuvC | TTE1373 | TTE1178 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | Holliday junction resolvasome endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.766 |
OraA | SbcD | TTE1373 | TTE0265 | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.683 |
PolA | OraA | TTE0874 | TTE1373 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Uncharacterized BCR; Modulates RecA activity; Belongs to the RecX family. | 0.757 |
PolA | QueA | TTE0874 | TTE1182 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.609 |
PolA | RecJ | TTE0874 | TTE1191 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Best Blastp hit = gi|7475820|pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis], score 390, E-value 1.00E-107. | 0.424 |
PolA | RuvA | TTE0874 | TTE1179 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Holliday junction resolvasome DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.747 |
PolA | RuvB | TTE0874 | TTE1180 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.825 |
PolA | RuvC | TTE0874 | TTE1178 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Holliday junction resolvasome endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.757 |
PolA | SbcD | TTE0874 | TTE0265 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
PolA | Tgt | TTE0874 | TTE1183 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Queuine/archaeosine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribos [...] | 0.441 |
PolA | YajC | TTE0874 | TTE1184 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Preprotein translocase subunit YajC; Best Blastp hit = gi|13634024|sp|Q9WZW3|Y859_THEMA HYPOTHETICAL PROTEIN TM0859 gi|7462565|pir||D72325 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981393|gb|AAD35941.1|AE001752_8 (AE001752) hypothetical protein [Thermotoga maritima], score 53.5, E-value 6.00E-07. | 0.613 |
QueA | PolA | TTE1182 | TTE0874 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.609 |
QueA | RecJ | TTE1182 | TTE1191 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Best Blastp hit = gi|7475820|pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis], score 390, E-value 1.00E-107. | 0.411 |
QueA | RuvA | TTE1182 | TTE1179 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Holliday junction resolvasome DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.876 |
QueA | RuvB | TTE1182 | TTE1180 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.920 |
QueA | RuvC | TTE1182 | TTE1178 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Holliday junction resolvasome endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.736 |