STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnjPredicted hydrolase of the metallo-beta-lactamase superfamily; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (554 aa)    
Predicted Functional Partners:
DapA
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.842
rny
Predicted HD superfamily hydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
  
 
 0.812
TTE1254
Conserved hypothetical protein; Best Blastp hit = gi|13621929|gb|AAK33694.1| (AE006527) conserved hypothetical protein [Streptococcus pyogenes], score 59.7, E-value 2.00E-08.
       0.799
FtsK
DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family.
 
    0.797
mltG
Predicted periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.716
SmtA3
SAM-dependent methyltransferases; Best Blastp hit = gi|7474470|pir||F69979 caffeoyl-CoA O-methyltransferase homolog yrrM - Bacillus subtilis gi|2635182|emb|CAB14678.1| (Z99117) similar to caffeoyl-CoA O-methyltransferase [Bacillus subtilis], score 134, E-value 1.00E-30.
       0.702
Fur3
Fe2+/Zn2+ uptake regulation proteins; Best Blastp hit = gi|10174144|dbj|BAB05246.1| (AP001512) ferric uptake regulation protein [Bacillus halodurans], score 117, E-value 8.00E-26; Belongs to the Fur family.
       0.700
TopA
Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...]
 
  
 0.679
BacA
Conserved hypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
      0.678
IspA
Best Blastp hit = gi|7447349|pir||S74538 geranylgeranyl pyrophosphate synthase - Synechocystis sp. (strain PCC 6803) gi|1651762|dbj|BAA16690.1| (D90899) geranylgeranyl pyrophosphate synthase [Synechocystis sp.], score 273, E-value 2.00E-72; Belongs to the FPP/GGPP synthase family.
  
    0.638
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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