STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XseAExonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (404 aa)    
Predicted Functional Partners:
XseB
Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
 
 0.999
FolD
5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
    0.986
IspA
Best Blastp hit = gi|7447349|pir||S74538 geranylgeranyl pyrophosphate synthase - Synechocystis sp. (strain PCC 6803) gi|1651762|dbj|BAA16690.1| (D90899) geranylgeranyl pyrophosphate synthase [Synechocystis sp.], score 273, E-value 2.00E-72; Belongs to the FPP/GGPP synthase family.
  
  
 0.932
NusB
Transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
 
    0.908
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.757
RecN
ATPases involved in DNA repair; May be involved in recombinational repair of damaged DNA.
 
   
 0.750
TTE1291
Conserved hypothetical protein; Best Blastp hit = gi|10175407|dbj|BAB06505.1| (AP001516) BH2786; unknown conserved protein [Bacillus halodurans], score 109, E-value 1.00E-23.
       0.687
TTE1283
Best Blastp hit = gi|730774|sp|Q01367|S3AA_BACSU STAGE III SPORULATION PROTEIN AA gi|98386|pir||S16622 stage III sporulation protein spoIIIAA - Bacillus subtilis gi|581722|emb|CAA43959.1| (X61962) SpoIIIAA protein [Bacillus subtilis] gi|1000359|gb|AAA76720.1| (U35252) SpoIIIAA [Bacillus subtilis] gi|1303904|dbj|BAA12560.1| (D84432) SpoIIIAA [Bacillus subtilis] gi|2634877|emb|CAB14374.1| (Z99116) spoIIIAA [Bacillus subtilis], score 257, E-value 2.00E-67.
       0.608
TTE1284
Best Blastp hit = gi|1710821|sp|Q01368|S3AB_BACSU STAGE III SPORULATION PROTEIN AB gi|7475863|pir||E69711 stage III sporulation protein spoIIIAB - Bacillus subtilis gi|1000360|gb|AAA76721.1| (U35252) SpoIIIAB [Bacillus subtilis] gi|1303905|dbj|BAA12561.1| (D84432) SpoIIIAB [Bacillus subtilis] gi|2634876|emb|CAB14373.1| (Z99116) spoIIIAB [Bacillus subtilis], score 100, E-value 9.00E-21.
       0.608
TTE1285
Hypothetical protein.
       0.608
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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