node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CheR2 | Hfq | TTE1355 | TTE1360 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.551 |
CheR2 | MiaA | TTE1355 | TTE1359 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.645 |
CheR2 | MiaB2 | TTE1355 | TTE1356 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | 2-methylthioadenine synthetase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.773 |
CheR2 | MutL | TTE1355 | TTE1358 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.634 |
CheR2 | MutS2 | TTE1355 | TTE1357 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.635 |
CheR2 | RnhA | TTE1355 | TTE1362 | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.433 |
DnaN | MutL | TTE0002 | TTE1358 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.993 |
DnaN | MutS2 | TTE0002 | TTE1357 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.906 |
DnaN | PolA | TTE0002 | TTE0874 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
DnaN | RnhA | TTE0002 | TTE1362 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.430 |
DnaN | TopA | TTE0002 | TTE1449 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.793 |
Hfq | CheR2 | TTE1360 | TTE1355 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | 0.551 |
Hfq | MiaA | TTE1360 | TTE1359 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.916 |
Hfq | MiaB2 | TTE1360 | TTE1356 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 2-methylthioadenine synthetase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.691 |
Hfq | MutL | TTE1360 | TTE1358 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.836 |
Hfq | MutS2 | TTE1360 | TTE1357 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.718 |
Hfq | PolA | TTE1360 | TTE0874 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.625 |
Hfq | RnhA | TTE1360 | TTE1362 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.648 |
MiaA | CheR2 | TTE1359 | TTE1355 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Methylase of chemotaxis methyl-accepting proteins; Best Blastp hit = gi|10174272|dbj|BAB05374.1| (AP001512) chemotaxis protein methyltransferase [Bacillus halodurans], score 247, E-value 1.00E-64. | 0.645 |
MiaA | Hfq | TTE1359 | TTE1360 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.916 |