STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsgAPredicted GTPases; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (295 aa)    
Predicted Functional Partners:
Thi80
Thiamine pyrophosphokinase; Best Blastp hit = gi|13701023|dbj|BAB42318.1| (AP003133) conserved hypothetical protein [Staphylococcus aureus] gi|13875537|dbj|BAB45779.1| (AP003361) conserved hypothetical protein [Staphylococcus aureus], score 76.3, E-value 3.00E-13.
  
 
 0.986
Rpe2
Pentose-5-phosphate-3-epimerase; Best Blastp hit = gi|10175122|dbj|BAB06221.1| (AP001515) ribulose-phosphate 3-epimerase [Bacillus halodurans], score 270, E-value 1.00E-71; Belongs to the ribulose-phosphate 3-epimerase family.
 
    0.969
Sps1
Serine/threonine protein kinase; Best Blastp hit = gi|10175124|dbj|BAB06223.1| (AP001515) serine/threonine protein kinase [Bacillus halodurans], score 319, E-value 7.00E-86; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
 
  
 0.957
Ptc1
Protein serine/threonine phosphatases; Best Blastp hit = gi|8895695|gb|AAF81068.1|AF223364_3 (AF223364) protein phosphatase 1 [Myxococcus xanthus], score 174, E-value 8.00E-43.
 
  
 0.924
ThiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
 0.908
Adk
Adenylate kinase and related kinases; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
Sun
tRNA and rRNA cytosine-C5-methylases; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.892
rlmN
Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.890
PriA
Primosomal protein N (replication factor Y) - superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.853
RpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
   0.834
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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