STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa)    
Predicted Functional Partners:
LysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.987
LysA2
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.986
MurE2
UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.941
ArgE2
Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Best Blastp hit = gi|7447174|pir||B69994 Xaa-His dipeptidase homolog ytjP - Bacillus subtilis gi|2293201|gb|AAC00279.1| (AF008220) putative peptidase [Bacillus subtilis] gi|2635482|emb|CAB14976.1| (Z99119) similar to Xaa-His dipeptidase [Bacillus subtilis], score 358, E-value 8.00E-98.
    
 0.939
CarB
Carbamoylphosphate synthase large subunit (split gene in MJ); Best Blastp hit = gi|1168772|sp|P46537|CARB_BACCL 'CARBAMOYL-PHOSPHATE SYNTHASE, PYRIMIDINE-SPECIFIC, LARGE CHAIN (CARBAMOYL-PHOSPHATE SYNTHETASE AMMONIA CHAIN)' gi|2118367|pir||I40169 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus gi|312443|emb|CAA51739.1| (X73308) carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus], score 1146, E-value 0.
    
 0.908
DapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
   
 0.901
DapA
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.883
Asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.882
LysC
Aspartokinases; Best Blastp hit = gi|10175020|dbj|BAB06119.1| (AP001515) aspartokinase I (alpha and beta subunits) [Bacillus halodurans], score 352, E-value 5.00E-96; Belongs to the aspartokinase family.
 
  
 0.805
TTE1513
Conserved hypothetical protein; Best Blastp hit = gi|7451793|pir||A69878 conserved hypothetical protein yloC - Bacillus subtilis gi|2337796|emb|CAA74270.1| (Y13937) YloC protein [Bacillus subtilis] gi|2633939|emb|CAB13440.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis], score 206, E-value 3.00E-52.
       0.761
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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