node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GuaA | GuaB | TTE0583 | TTE0582 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
GuaA | IleS | TTE0583 | TTE1594 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.787 |
GuaA | LeuS | TTE0583 | TTE0324 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Leucyl-tRNA synthetase; Best Blastp hit = gi|6919980|sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS) gi|7437543|pir||F72408 leucine--tRNA ligase (EC 6.1.1.4) - Thermotoga maritima (strain MSB8) gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702) leucyl-tRNA synthetase [Thermotoga maritima], score 840, E-value 0; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.704 |
GuaA | MetG | TTE0583 | TTE0110 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.872 |
GuaA | PheS | TTE0583 | TTE1689 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Best Blastp hit = gi|2507429|sp|P17921|SYFA_BACSU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE--TRNA LIGASE ALPHA CHAIN) (PHERS) gi|7428485|pir||YFBSA phenylalanine--tRNA ligase (EC 6.1.1.20) alpha chain - Bacillus subtilis gi|1770030|emb|CAA99603.1| (Z75208) phenylalany-tRNA synthetase beta subunit [Bacillus subtilis] gi|2635329|emb|CAB14824.1| (Z99118) phenylalanyl-tRNA synthetase (alpha subunit) [Bacillus subtilis], score 421, E-value 1.00E-117; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.749 |
GuaA | PheT | TTE0583 | TTE1688 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Best Blastp hit = gi|3123292|sp|P17922|SYFB_BACSU PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE--TRNA LIGASE BETA CHAIN) (PHERS) gi|7428487|pir||YFBSB phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain - Bacillus subtilis gi|1770031|emb|CAA99564.1| (Z75208) phenylalanyl-tRNA synthetase beta subunit [Bacillus subtilis] gi|2635328|emb|CAB14823.1| (Z99118) phenylalanyl-tRNA synthetase (beta subunit) [Bacillus subtilis], score 591, E-value 1.00E-167. | 0.947 |
GuaA | RpoB | TTE0583 | TTE2301 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta subunit/140 kD subunit (split gene in Mjan, Mthe, Aful); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.948 |
GuaA | RpsB | TTE0583 | TTE1409 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S2; Best Blastp hit = gi|10175047|dbj|BAB06146.1| (AP001515) 30S ribosomal protein S2 [Bacillus halodurans], score 367, E-value 1.00E-100; Belongs to the universal ribosomal protein uS2 family. | 0.789 |
GuaA | RpsC | TTE0583 | TTE2286 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.814 |
GuaB | GuaA | TTE0582 | TTE0583 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
GuaB | IleS | TTE0582 | TTE1594 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.557 |
GuaB | LeuS | TTE0582 | TTE0324 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Leucyl-tRNA synthetase; Best Blastp hit = gi|6919980|sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS) gi|7437543|pir||F72408 leucine--tRNA ligase (EC 6.1.1.4) - Thermotoga maritima (strain MSB8) gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702) leucyl-tRNA synthetase [Thermotoga maritima], score 840, E-value 0; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.428 |
GuaB | MetG | TTE0582 | TTE0110 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.820 |
GuaB | PheT | TTE0582 | TTE1688 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Best Blastp hit = gi|3123292|sp|P17922|SYFB_BACSU PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE--TRNA LIGASE BETA CHAIN) (PHERS) gi|7428487|pir||YFBSB phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain - Bacillus subtilis gi|1770031|emb|CAA99564.1| (Z75208) phenylalanyl-tRNA synthetase beta subunit [Bacillus subtilis] gi|2635328|emb|CAB14823.1| (Z99118) phenylalanyl-tRNA synthetase (beta subunit) [Bacillus subtilis], score 591, E-value 1.00E-167. | 0.948 |
GuaB | RpoB | TTE0582 | TTE2301 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA-directed RNA polymerase beta subunit/140 kD subunit (split gene in Mjan, Mthe, Aful); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.925 |
GuaB | RpsB | TTE0582 | TTE1409 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribosomal protein S2; Best Blastp hit = gi|10175047|dbj|BAB06146.1| (AP001515) 30S ribosomal protein S2 [Bacillus halodurans], score 367, E-value 1.00E-100; Belongs to the universal ribosomal protein uS2 family. | 0.802 |
GuaB | RpsC | TTE0582 | TTE2286 | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.659 |
IleS | GuaA | TTE1594 | TTE0583 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.787 |
IleS | GuaB | TTE1594 | TTE0582 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.557 |
IleS | LeuS | TTE1594 | TTE0324 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Leucyl-tRNA synthetase; Best Blastp hit = gi|6919980|sp|Q9WY15|SYL_THEMA LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE) (LEURS) gi|7437543|pir||F72408 leucine--tRNA ligase (EC 6.1.1.4) - Thermotoga maritima (strain MSB8) gi|4980663|gb|AAD35261.1|AE001702_1 (AE001702) leucyl-tRNA synthetase [Thermotoga maritima], score 840, E-value 0; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.948 |