STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE1694Conserved hypothetical protein; Best Blastp hit = gi|2128945|pir||A64496 hypothetical protein MJ1570 - Methanococcus jannaschii gi|1500464|gb|AAB99594.1| (U67597) M. jannaschii predicted coding region MJ1570 [Methanococcus jannaschii], score 62, E-value 2.00E-09. (105 aa)    
Predicted Functional Partners:
CbiM2
Best Blastp hit = gi|2127816|pir||H64495 cobalamin biosynthesis protein M - Methanococcus jannaschii gi|1592191|gb|AAB99587.1| (U67597) cobalamin biosynthesis protein (cbiM) [Methanococcus jannaschii], score 203, E-value 1.00E-51.
  
  0.995
CbiQ
ABC-type cobalt transport system, permease component CbiQ and related transporters; Best Blastp hit = gi|2128946|pir||B64496 hypothetical protein MJ1571 - Methanococcus jannaschii gi|1592192|gb|AAB99588.1| (U67597) cobalt transport protein (cbiQ) [Methanococcus jannaschii], score 145, E-value 8.00E-34.
 
 0.983
CbiO
ABC-type cobalt transport system, ATPase component; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 0.973
CbiM
Best Blastp hit = gi|2127816|pir||H64495 cobalamin biosynthesis protein M - Methanococcus jannaschii gi|1592191|gb|AAB99587.1| (U67597) cobalamin biosynthesis protein (cbiM) [Methanococcus jannaschii], score 192, E-value 4.00E-48.
  
  0.968
TTE0248
Conserved hypothetical protein; Best Blastp hit = gi|2128945|pir||A64496 hypothetical protein MJ1570 - Methanococcus jannaschii gi|1500464|gb|AAB99594.1| (U67597) M. jannaschii predicted coding region MJ1570 [Methanococcus jannaschii], score 50.4, E-value 7.00E-06.
  
  
 
0.901
CbiQ2
ABC-type cobalt transport system, permease component CbiQ and related transporters; Best Blastp hit = gi|7518348|pir||F75200 hypothetical protein PAB2261 - Pyrococcus abyssi (strain Orsay) gi|5457562|emb|CAB49053.1| (AJ248283) hypothetical protein [Pyrococcus abyssi], score 110, E-value 2.00E-23.
  
 
 0.670
CbiQ3
ABC-type cobalt transport system, permease component CbiQ and related transporters; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
 
 0.670
HyaD
Ni,Fe-hydrogenase maturation factor; Best Blastp hit = gi|1093502|prf||2104213J protease HycI [Escherichia coli], score 135, E-value 4.00E-31.
       0.574
TTE1697
Best Blastp hit = gi|123922|sp|P16434|HYCH_ECOLI FORMATE HYDROGENLYASE MATURATION PROTEIN HYCH gi|78778|pir||S08626 formate hydrogenlyase maturation protein - Escherichia coli gi|41687|emb|CAA35553.1| (X17506) hycH [Escherichia coli] gi|882611|gb|AAA69228.1| (U29579) formate hydrogenlyase maturation protein [Escherichia coli] gi|1789073|gb|AAC75760.1| (AE000356) processing of large subunit (HycE) of hydrogenase 3 (part of the FHL complex) [Escherichia coli K12] gi|13363045|dbj|BAB36997.1| (AP002562) formate hydrogenlyase maturation protein [Escherichia coli O157:H7] gi|1093501|prf||210 [...]
       0.574
TTE1698
Ni,Fe-hydrogenase III small subunit; Best Blastp hit = gi|2506958|sp|P16433|HYCG_ECOLI FORMATE HYDROGENLYASE SUBUNIT 7 (FHL SUBUNIT 7) (HYDROGENASE-3 COMPONENT G) gi|78777|pir||S08625 hydrogenase (EC 1.18.99.1) 3 chain 7 - Escherichia coli gi|882612|gb|AAA69229.1| (U29579) formate hydrogenlyase subunit 7 [Escherichia coli] gi|1789074|gb|AAC75761.1| (AE000356) hydrogenase activity [Escherichia coli K12], score 274, E-value 1.00E-72.
       0.558
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
Server load: low (28%) [HD]