STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (521 aa)    
Predicted Functional Partners:
PpsA2
Best Blastp hit = gi|10720401|sp|P22983|PODK_CLOSY 'PYRUVATE,PHOSPHATE DIKINASE (PYRUVATE,ORTHOPHOSPHATE DIKINASE)', score 1194, E-value 0; Belongs to the PEP-utilizing enzyme family.
     
 0.948
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
    
 0.938
Eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.918
PycA
Pyruvate carboxylase, C-terminal domain/subunit; Best Blastp hit = gi|6685821|sp|Q58628|PYCB_METJA PYRUVATE CARBOXYLASE SUBUNIT B (PYRUVIC CARBOXYLASE B) gi|2129173|pir||F64453 oxaloacetate decarboxylase (EC 4.1.1.3) alpha chain MJ1231 [similarity] - Methanococcus jannaschii gi|1591862|gb|AAB99233.1| (U67563) oxaloacetate decarboxylase alpha chain (oadA) [Methanococcus jannaschii], score 588, E-value 1.00E-167.
    
 0.911
PycA2
Pyruvate carboxylase, C-terminal domain/subunit; Best Blastp hit = gi|6685821|sp|Q58628|PYCB_METJA PYRUVATE CARBOXYLASE SUBUNIT B (PYRUVIC CARBOXYLASE B) gi|2129173|pir||F64453 oxaloacetate decarboxylase (EC 4.1.1.3) alpha chain MJ1231 [similarity] - Methanococcus jannaschii gi|1591862|gb|AAB99233.1| (U67563) oxaloacetate decarboxylase alpha chain (oadA) [Methanococcus jannaschii], score 589, E-value 1.00E-167.
    
 0.911
PpsA
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Best Blastp hit = gi|7521303|pir||E72754 probable phosphoenolpyruvate synthase APE0026 - Aeropyrum pernix (strain K1) gi|5103414|dbj|BAA78935.1| (AP000058) 622aa long hypothetical phosphoenolpyruvate synthase [Aeropyrum pernix], score 68.2, E-value 3.00E-10.
     
 0.908
OadB
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.907
OadB2
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.907
OadB3
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.907
AspA
Aspartate ammonia-lyase; Best Blastp hit = gi|10174043|dbj|BAB05145.1| (AP001512) aspartate ammonia-lyase [Bacillus halodurans], score 426, E-value 1.00E-118.
   
 
 0.898
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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