STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)    
Predicted Functional Partners:
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
 
 0.999
Pgi
Glucose-6-phosphate isomerase; Best Blastp hit = gi|120717|sp|P13375|G6PA_BACST GLUCOSE-6-PHOSPHATE ISOMERASE A (GPI A) (PHOSPHOGLUCOSE ISOMERASE A) (PGI-A) gi|68452|pir||NUBSSA glucose-6-phosphate isomerase (EC 5.3.1.9) A [validated] - Bacillus stearothermophilus gi|40046|emb|CAA34634.1| (X16639) phosphoglucose isomerase A (AA 1-449) [Bacillus stearothermophilus], score 617, E-value 1.00E-176.
  
 0.996
GuaA
GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.976
Fba
Fructose/tagatose bisphosphate aldolase; Best Blastp hit = gi|6652729|gb|AAF22441.1|AF052204_1 '(AF052204) fructose-1,6-bisphosphate aldolase [Thermus aquaticus]', score 313, E-value 2.00E-84.
 
 
 0.963
MipB
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.942
TktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.934
FruK
Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Best Blastp hit = gi|11259262|pir||C82450 1-phosphofructokinase VCA0517 [imported] - Vibrio cholerae (group O1 strain N16961) gi|9657922|gb|AAF96420.1| (AE004382) 1-phosphofructokinase [Vibrio cholerae], score 169, E-value 3.00E-41; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.927
ManA
Phosphomannose isomerase; Best Blastp hit = gi|13249157|gb|AAK16707.1| (AF324506) mannose-6-phosphate isomerase [Bacillus subtilis], score 211, E-value 8.00E-54.
 
  
 0.926
Eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.920
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
     
 0.918
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.