STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UxaCGlucuronate isomerase; Best Blastp hit = gi|7531226|sp|O34808|UXAC_BACSU URONATE ISOMERASE (GLUCURONATE ISOMERASE) (URONIC ISOMERASE) gi|7474860|pir||C69852 glucuronate isomerase homolog yjmA - Bacillus subtilis gi|2612902|gb|AAC46326.1| (AF015825) hypothetical uronate isomerase [Bacillus subtilis] gi|2633584|emb|CAB13087.1| (Z99110) similar to glucuronate isomerase [Bacillus subtilis], score 647, E-value 0. (466 aa)    
Predicted Functional Partners:
MtlD2
Mannitol-1-phosphate/altronate dehydrogenases; Best Blastp hit = gi|7462737|pir||H72422 hypothetical protein TM0068 - Thermotoga maritima (strain MSB8) gi|4980555|gb|AAD35162.1|AE001693_8 '(AE001693) D-mannonate oxidoreductase, putative [Thermotoga maritima]', score 670, E-value 0.
 
 
 0.997
TTE1944
Conserved hypothetical protein; Best Blastp hit = gi|7452102|pir||C72377 hypothetical protein TM0440 - Thermotoga maritima (strain MSB8) gi|4980947|gb|AAD35525.1|AE001722_9 (AE001722) hypothetical protein [Thermotoga maritima], score 321, E-value 1.00E-86.
 
  
 0.966
TTE1934
Alpha-glucosidases, family 31 of glycosyl hydrolases; Best Blastp hit = gi|10173318|dbj|BAB04423.1| (AP001509) glucosidase [Bacillus halodurans], score 846, E-value 0; Belongs to the glycosyl hydrolase 31 family.
 
   
 0.717
MtlD
Mannitol-1-phosphate/altronate dehydrogenases; Best Blastp hit = gi|8134573|sp|O65992|MTLD_CLOAB MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE gi|3025457|gb|AAC12851.1| (U53868) MtlD [Clostridium acetobutylicum], score 404, E-value 1.00E-111.
 
  
 0.684
XylB
Sugar (pentulose and hexulose) kinases; Best Blastp hit = gi|12725247|gb|AAK06282.1|AE006447_3 (AE006447) gluconate kinase (EC 2.7.1.12) [Lactococcus lactis subsp. lactis], score 250, E-value 3.00E-65; Belongs to the FGGY kinase family.
     
 0.683
UgpB4
Sugar-binding periplasmic proteins/domains; Best Blastp hit = gi|7462766|pir||C72376 hypothetical protein TM0432 - Thermotoga maritima (strain MSB8) gi|4980939|gb|AAD35517.1|AE001722_1 '(AE001722) sugar ABC transporter, periplasmic sugar-binding protein, putative [Thermotoga maritima]', score 129, E-value 8.00E-29.
  
  
 0.538
MelB
Na+/melibiose symporter and related transporters; Best Blastp hit = gi|6136458|sp|P96792|XYLP_LACPE PUTATIVE XYLOSE-PROTON SYMPORTER (XYLOSE TRANSPORTER) gi|3688059|gb|AAC62250.1| (U89276) isoprimeverose cation-symporter XylP [Lactobacillus pentosus], score 150, E-value 3.00E-35.
     
 0.518
GalK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
     
 0.485
Gnd2
6-phosphogluconate dehydrogenase, family 1; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
 0.484
LdhA
Lactate dehydrogenase and related dehydrogenases; Best Blastp hit = gi|13516509|dbj|BAB40320.1| (AB033995) glyoxylate reductase [Thermococcus litoralis], score 174, E-value 1.00E-42; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.453
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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