STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE1956Conserved hypothetical protein; Best Blastp hit = gi|7462126|pir||B72239 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4982118|gb|AAD36617.1|AE001801_4 (AE001801) conserved hypothetical protein [Thermotoga maritima], score 189, E-value 6.00E-47. (458 aa)    
Predicted Functional Partners:
PflA2
Pyruvate-formate lyase-activating enzyme; Best Blastp hit = gi|7445247|pir||C72239 hypothetical protein TM1552 - Thermotoga maritima (strain MSB8) gi|4982119|gb|AAD36618.1|AE001801_5 '(AE001801) pyruvate formate-lyase activating enzyme, putative [Thermotoga maritima]', score 354, E-value 8.00E-97.
     0.971
TTE1957
Predicted nucleotidyltransferases; Best Blastp hit = gi|13814886|gb|AAK41854.1| (AE006778) Conserved hypothetical protein [Sulfolobus solfataricus], score 53.1, E-value 1.00E-06.
       0.542
TTE1958
Conserved hypothetical protein; Best Blastp hit = gi|7450154|pir||C71115 hypothetical protein PH0690 - Pyrococcus horikoshii gi|3257098|dbj|BAA29781.1| (AP000003) 128aa long hypothetical protein [Pyrococcus horikoshii], score 52.8, E-value 2.00E-06.
       0.542
TTE1954
Hypothetical protein.
       0.541
LigT
3'-5' RNA Ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.503
TTE2697
Uncharacterized FAD-dependent dehydrogenases; Best Blastp hit = gi|10174087|dbj|BAB05189.1| (AP001512) BH1470; unknown conserved protein in others [Bacillus halodurans], score 450, E-value 1.00E-125.
 
     0.498
nnrE
Predicted sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both e [...]
  
  
 0.486
TTE1953
Hypothetical protein.
       0.440
NadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
       0.403
TTE1181
Conserved hypothetical protein; Best Blastp hit = gi|7462519|pir||C72337 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981301|gb|AAD35855.1|AE001746_16 (AE001746) hypothetical protein [Thermotoga maritima], score 56.6, E-value 5.00E-08.
       0.403
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.