STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
KdpCK+-transporting ATPase, c chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (193 aa)    
Predicted Functional Partners:
KdpB
High-affinity K+ transport system, ATPase chain B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 0.999
KdpA
K+-transporting ATPase, A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
 0.999
KdpD
Osmosensitive K+ channel His kinase sensor domain protein; Best Blastp hit = gi|11281914|pir||T46849 K+-transporting ATPase (EC 3.6.1.-) chain D' [imported] - Anabaena sp gi|6635817|gb|AAF19990.1|AF213466_5 (AF213466) potassium-dependent ATPase subunit D' [Anabaena sp. L-31], score 312, E-value 4.00E-84.
 
  
 0.980
KdpD2
Osmosensitive K+ channel His kinase sensor domain protein; Best Blastp hit = gi|13472735|ref|NP_104302.1| two-component sensor KdpD [Mesorhizobium loti] gi|14023482|dbj|BAB50088.1| (AP003001) two-component sensor; KdpD [Mesorhizobium loti], score 366, E-value 1.00E-100.
 
  
 0.957
TTE2211
Conserved hypothetical protein; Best Blastp hit = gi|3122321|sp|P96372|KDPD_MYCTU SENSOR PROTEIN KDPD gi|7478949|pir||G70623 probable sensor protein kdpd - Mycobacterium tuberculosis (strain H37RV) gi|1870000|emb|CAB06851.1| (Z92539) kdpD [Mycobacterium tuberculosis], score 50.8, E-value 7.00E-06.
 
  
 0.757
TTE2007
Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
       0.746
TTE2008
Hypothetical protein.
       0.746
Cda1.3
Predicted xylanase/chitin deacetylase; Best Blastp hit = gi|10173510|dbj|BAB04614.1| (AP001510) polysaccharide deacetylase (nodulation protein NodB) [Bacillus halodurans], score 247, E-value 1.00E-64.
  
    0.589
mprF
Predicted integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.579
BaeS11
Sensory transduction histidine kinases; Best Blastp hit = gi|10174563|dbj|BAB05664.1| (AP001513) two-component sensor histidine kinase [Bacillus halodurans], score 221, E-value 2.00E-56.
  
  
 0.560
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.