STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NemA3NADH:flavin oxidoreductases, Old Yellow Enzyme family; Best Blastp hit = gi|479960|pir||S35706 NADH oxidase (EC 1.-.-.-) - Thermoanaerobacter brockii, score 517, E-value 1.00E-145. (647 aa)    
Predicted Functional Partners:
TTE2338
Conserved hypothetical protein; Best Blastp hit = gi|11349142|pir||A83493 hypothetical protein PA1234 [imported] - Pseudomonas aeruginosa (strain PAO1) gi|9947163|gb|AAG04623.1|AE004552_13 (AE004552) hypothetical protein [Pseudomonas aeruginosa], score 55.8, E-value 3.00E-07.
  
 0.892
FixA
Best Blastp hit = gi|2829835|sp|P97089|ETFB_CLOTS ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT (BETA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN SMALL SUBUNIT) (ETFSS) gi|11250239|pir||T45287 electron transfer flavoprotein beta chain [imported] - Clostridium thermosaccharolyticum gi|1903329|emb|CAB07497.1| (Z92974) electron transfer flavoprotein beta-subunit [Thermoanaerobacterium thermosaccharolyticum], score 394, E-value 1.00E-109.
  
 
 0.847
AcoB
Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit; Best Blastp hit = gi|10173391|dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain [Bacillus halodurans], score 385, E-value 1.00E-106.
  
 0.773
AcoB2
Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit; Best Blastp hit = gi|13814759|gb|AAK41749.1| '(AE006767) Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2) [Sulfolobus solfataricus]', score 400, E-value 1.00E-110.
  
 0.773
AceF
Dihydrolipoamide acyltransferases; Best Blastp hit = gi|10173392|dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans], score 269, E-value 4.00E-71.
  
 0.767
AceF2
Dihydrolipoamide acyltransferases; Best Blastp hit = gi|10174442|dbj|BAB05543.1| (AP001513) acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Bacillus halodurans], score 227, E-value 2.00E-58.
  
 0.767
AceF3
Dihydrolipoamide acyltransferases; Best Blastp hit = gi|13814762|gb|AAK41752.1| '(AE006767) Dihydrolipoamide S-acetyltransferase, carboxy-end (pdhC) [Sulfolobus solfataricus]', score 187, E-value 1.00E-46.
  
 0.767
GrxC
Glutaredoxin and related proteins; Best Blastp hit = gi|7451278|pir||F72303 glutaredoxin - Thermotoga maritima (strain MSB8) gi|4981572|gb|AAD36108.1|AE001764_11 (AE001764) glutaredoxin [Thermotoga maritima], score 90.9, E-value 1.00E-17.
  
 
 0.761
FixB
Best Blastp hit = gi|2829489|sp|P71153|ETFA_CLOTS ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT (ALPHA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN LARGE SUBUNIT) (ETFLS) gi|11250211|pir||T45288 electron transfer flavoprotein alpha chain [imported] - Clostridium thermosaccharolyticum gi|1667354|emb|CAB04791.1| (Z82038) electron-transfer flavoprotein alpha-subunit [Thermoanaerobacterium thermosaccharolyticum] gi|1903330|emb|CAB07498.1| (Z92974) electron transfer flavoprotein alpha-subunit [Thermoanaerobacterium thermosaccharolyticum], score 437, E-value 1.00E-122.
  
 
 0.733
GuaB
IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.688
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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