node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CheY7 | RpoD2 | TTE1304 | TTE1636 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.889 |
CheY7 | RsbU | TTE1304 | TTE2396 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Serine phosphatase RsbU, regulator of sigma subunit; Best Blastp hit = gi|586018|sp|P37475|SP2E_BACSU STAGE II SPORULATION PROTEIN E gi|2127240|pir||S66094 stage II sporulation protein SpoIIE - Bacillus subtilis gi|467453|dbj|BAA05299.1| (D26185) stage II sporulation [Bacillus subtilis] gi|857493|gb|AAB58073.1| (U26835) SpoIIE [Bacillus subtilis] gi|2632331|emb|CAB11840.1| (Z99104) serine phosphatase [Bacillus subtilis] gi|1588992|prf||2209421A spollE gene [Bacillus subtilis], score 299, E-value 1.00E-79. | 0.860 |
CheY7 | RsbW3 | TTE1304 | TTE1316 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma regulatory factor (Ser/Thr protein kinase); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.881 |
CheY7 | SpoIIAA | TTE1304 | TTE1315 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Best Blastp hit = gi|10174153|dbj|BAB05255.1| (AP001512) anti-sigma F factor antagonist (stage II sporulation protein AA) [Bacillus halodurans], score 100, E-value 5.00E-21; Belongs to the anti-sigma-factor antagonist family. | 0.780 |
CheY7 | TTE0170 | TTE1304 | TTE0170 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Transcription regulator of sigma-E/sigma-K-dependent gene spoIIID; Best Blastp hit = gi|134766|sp|P15281|SP3D_BACSU STAGE III SPORULATION PROTEIN D (14 KD TRANSCRIPTION FACTOR) gi|98493|pir||A33472 transcription regulator of sigma-E/sigma-K-dependent gene spoIIID - Bacillus subtilis gi|580763|emb|CAA33541.1| (X15520) transcription factor (AA 1-93) [Bacillus subtilis] gi|580931|emb|CAA36295.1| (X52076) spoIIID protein (AA 1-93) [Bacillus subtilis] gi|1684653|emb|CAB05384.1| (Z82987) SpoIIID [Bacillus subtilis] gi|2636167|emb|CAB15659.1| (Z99122) transcriptional regulator [Bacillus subti [...] | 0.870 |
CheY7 | TTE1283 | TTE1304 | TTE1283 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Best Blastp hit = gi|730774|sp|Q01367|S3AA_BACSU STAGE III SPORULATION PROTEIN AA gi|98386|pir||S16622 stage III sporulation protein spoIIIAA - Bacillus subtilis gi|581722|emb|CAA43959.1| (X61962) SpoIIIAA protein [Bacillus subtilis] gi|1000359|gb|AAA76720.1| (U35252) SpoIIIAA [Bacillus subtilis] gi|1303904|dbj|BAA12560.1| (D84432) SpoIIIAA [Bacillus subtilis] gi|2634877|emb|CAB14374.1| (Z99116) spoIIIAA [Bacillus subtilis], score 257, E-value 2.00E-67. | 0.797 |
CheY7 | TTE1616 | TTE1304 | TTE1616 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.866 |
CheY7 | TTE1638 | TTE1304 | TTE1638 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Sporulation specific protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.717 |
CheY7 | TTE2552 | TTE1304 | TTE2552 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | pro-sigma-E processing factor spoIIR; Best Blastp hit = gi|730770|sp|P39151|SP2R_BACSU STAGE II SPORULATION PROTEIN R gi|2127223|pir||I40474 pro-sigma-E processing factor spoIIR - Bacillus subtilis gi|556879|emb|CAA86103.1| (Z38002) Unknown [Bacillus subtilis] gi|2636222|emb|CAB15714.1| '(Z99122) alternate gene name: ipc-27d, csfX [Bacillus subtilis]' gi|1095417|prf||2108403B spoIIR gene [Bacillus subtilis], score 120, E-value 1.00E-26. | 0.832 |
CheY7 | TTE2563 | TTE1304 | TTE2563 | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Transcription regulator spoVT; Best Blastp hit = gi|586883|sp|P37554|SP5T_BACSU STAGE V SPORULATION PROTEIN T gi|2126881|pir||S66086 AbrB homolog - Bacillus subtilis gi|7475924|pir||F69716 transcription regulator spoVT - Bacillus subtilis gi|467445|dbj|BAA05291.1| (D26185) similar to AbrB [Bacillus subtilis] gi|2632323|emb|CAB11832.1| (Z99104) transcriptional regulator [Bacillus subtilis], score 201, E-value 5.00E-51. | 0.849 |
RpoD2 | CheY7 | TTE1636 | TTE1304 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | CheY-like receiver domains; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.889 |
RpoD2 | RsbU | TTE1636 | TTE2396 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Serine phosphatase RsbU, regulator of sigma subunit; Best Blastp hit = gi|586018|sp|P37475|SP2E_BACSU STAGE II SPORULATION PROTEIN E gi|2127240|pir||S66094 stage II sporulation protein SpoIIE - Bacillus subtilis gi|467453|dbj|BAA05299.1| (D26185) stage II sporulation [Bacillus subtilis] gi|857493|gb|AAB58073.1| (U26835) SpoIIE [Bacillus subtilis] gi|2632331|emb|CAB11840.1| (Z99104) serine phosphatase [Bacillus subtilis] gi|1588992|prf||2209421A spollE gene [Bacillus subtilis], score 299, E-value 1.00E-79. | 0.836 |
RpoD2 | RsbW3 | TTE1636 | TTE1316 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma regulatory factor (Ser/Thr protein kinase); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.840 |
RpoD2 | SpoIIAA | TTE1636 | TTE1315 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Best Blastp hit = gi|10174153|dbj|BAB05255.1| (AP001512) anti-sigma F factor antagonist (stage II sporulation protein AA) [Bacillus halodurans], score 100, E-value 5.00E-21; Belongs to the anti-sigma-factor antagonist family. | 0.717 |
RpoD2 | TTE0170 | TTE1636 | TTE0170 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcription regulator of sigma-E/sigma-K-dependent gene spoIIID; Best Blastp hit = gi|134766|sp|P15281|SP3D_BACSU STAGE III SPORULATION PROTEIN D (14 KD TRANSCRIPTION FACTOR) gi|98493|pir||A33472 transcription regulator of sigma-E/sigma-K-dependent gene spoIIID - Bacillus subtilis gi|580763|emb|CAA33541.1| (X15520) transcription factor (AA 1-93) [Bacillus subtilis] gi|580931|emb|CAA36295.1| (X52076) spoIIID protein (AA 1-93) [Bacillus subtilis] gi|1684653|emb|CAB05384.1| (Z82987) SpoIIID [Bacillus subtilis] gi|2636167|emb|CAB15659.1| (Z99122) transcriptional regulator [Bacillus subti [...] | 0.803 |
RpoD2 | TTE1283 | TTE1636 | TTE1283 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Best Blastp hit = gi|730774|sp|Q01367|S3AA_BACSU STAGE III SPORULATION PROTEIN AA gi|98386|pir||S16622 stage III sporulation protein spoIIIAA - Bacillus subtilis gi|581722|emb|CAA43959.1| (X61962) SpoIIIAA protein [Bacillus subtilis] gi|1000359|gb|AAA76720.1| (U35252) SpoIIIAA [Bacillus subtilis] gi|1303904|dbj|BAA12560.1| (D84432) SpoIIIAA [Bacillus subtilis] gi|2634877|emb|CAB14374.1| (Z99116) spoIIIAA [Bacillus subtilis], score 257, E-value 2.00E-67. | 0.757 |
RpoD2 | TTE1616 | TTE1636 | TTE1616 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.829 |
RpoD2 | TTE1638 | TTE1636 | TTE1638 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation specific protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.945 |
RpoD2 | TTE2552 | TTE1636 | TTE2552 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | pro-sigma-E processing factor spoIIR; Best Blastp hit = gi|730770|sp|P39151|SP2R_BACSU STAGE II SPORULATION PROTEIN R gi|2127223|pir||I40474 pro-sigma-E processing factor spoIIR - Bacillus subtilis gi|556879|emb|CAA86103.1| (Z38002) Unknown [Bacillus subtilis] gi|2636222|emb|CAB15714.1| '(Z99122) alternate gene name: ipc-27d, csfX [Bacillus subtilis]' gi|1095417|prf||2108403B spoIIR gene [Bacillus subtilis], score 120, E-value 1.00E-26. | 0.841 |
RpoD2 | TTE2563 | TTE1636 | TTE2563 | DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcription regulator spoVT; Best Blastp hit = gi|586883|sp|P37554|SP5T_BACSU STAGE V SPORULATION PROTEIN T gi|2126881|pir||S66086 AbrB homolog - Bacillus subtilis gi|7475924|pir||F69716 transcription regulator spoVT - Bacillus subtilis gi|467445|dbj|BAA05291.1| (D26185) similar to AbrB [Bacillus subtilis] gi|2632323|emb|CAB11832.1| (Z99104) transcriptional regulator [Bacillus subtilis], score 201, E-value 5.00E-51. | 0.793 |