STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DdlA2D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. (389 aa)    
Predicted Functional Partners:
MurF
UDP-N-acetylmuramyl pentapeptide synthase; Best Blastp hit = gi|7464026|pir||C71903 D-alanyl-D-alanine-adding enzyme - Helicobacter pylori (strain J99) gi|4155222|gb|AAD06244.1| (AE001499) D-ALANYL-D-ALANINE-ADDING ENZYME [Helicobacter pylori J99], score 212, E-value 1.00E-53.
 
 0.998
MurC
UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.988
MurB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.979
Alr2
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.954
Alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.953
MurG
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.920
DdlA
D-alanine-D-alanine ligase and related ATP-grasp enzymes; Best Blastp hit = gi|2494029|sp|P55650|Y4SG_RHISN HYPOTHETICAL 37.0 KD PROTEIN Y4SG gi|2182621|gb|AAB91846.1| (AE000096) Y4sG [Rhizobium sp. NGR234], score 117, E-value 2.00E-25.
     
 
0.900
MhpC4
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Best Blastp hit = gi|7433089|pir||H69838 chloride peroxidase homolog yisY - Bacillus subtilis gi|2145391|emb|CAA70654.1| (Y09476) YisY [Bacillus subtilis] gi|2633426|emb|CAB12930.1| (Z99109) similar to chloride peroxidase [Bacillus subtilis], score 96.3, E-value 5.00E-19.
 
   
 0.817
FtsI
Best Blastp hit = gi|11350727|pir||G83146 penicillin-binding protein 2 PA4003 [imported] - Pseudomonas aeruginosa (strain PAO1) gi|4887203|gb|AAD32230.1|AF147448_1 (AF147448) penicillin-binding protein 2 [Pseudomonas aeruginosa] gi|9950195|gb|AAG07390.1|AE004817_14 (AE004817) penicillin-binding protein 2 [Pseudomonas aeruginosa], score 197, E-value 3.00E-49.
 
 
 0.708
MurD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.706
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.