STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SurA2Parvulin-like peptidyl-prolyl isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (306 aa)    
Predicted Functional Partners:
Mfd
Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.732
Pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
     
 0.728
TTE2566
Hypothetical protein.
       0.717
TTE2563
Transcription regulator spoVT; Best Blastp hit = gi|586883|sp|P37554|SP5T_BACSU STAGE V SPORULATION PROTEIN T gi|2126881|pir||S66086 AbrB homolog - Bacillus subtilis gi|7475924|pir||F69716 transcription regulator spoVT - Bacillus subtilis gi|467445|dbj|BAA05291.1| (D26185) similar to AbrB [Bacillus subtilis] gi|2632323|emb|CAB11832.1| (Z99104) transcriptional regulator [Bacillus subtilis], score 201, E-value 5.00E-51.
     
 0.629
GuaB
IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.598
DegQ2
Trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain; Best Blastp hit = gi|6063141|gb|AAF03153.1|AF188296_1 (AF188296) HtrA-like serine protease [Bacillus subtilis], score 225, E-value 8.00E-58.
     
 0.542
YidC
Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
 
  
 0.478
ClpP
Protease subunit of ATP-dependent Clp proteases; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.473
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
   
 
 0.455
TTE2562
Conserved hypothetical protein; Best Blastp hit = gi|586878|sp|P37548|YABG_BACSU HYPOTHETICAL 33.3 KD PROTEIN IN KSGA-VEG INTERGENIC REGION gi|2127036|pir||S66072 yabG protein - Bacillus subtilis gi|467432|dbj|BAA05278.1| (D26185) unknown [Bacillus subtilis] gi|2632310|emb|CAB11819.1| (Z99104) yabG [Bacillus subtilis], score 234, E-value 8.00E-61.
       0.444
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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