STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MutT4NTP pyrophosphohydrolases including oxidative damage repair enzymes; Best Blastp hit = gi|2641974|dbj|BAA23614.1| (AB005149) orf2 [Exiguobacterium acetylicum], score 64.7, E-value 6.00E-10. (148 aa)    
Predicted Functional Partners:
Spo0J5
Predicted Transcriptional regulator; Best Blastp hit = gi|10176684|dbj|BAB07778.1| (AP001520) DNA-binding protein Spo0J-like homolog [Bacillus halodurans], score 222, E-value 5.00E-57; Belongs to the ParB family.
       0.592
Soj
ATPases involved in chromosome partitioning; Best Blastp hit = gi|586852|sp|P37522|SOJ_BACSU SPORULATION INITIATION INHIBITOR PROTEIN SOJ gi|2127177|pir||I40444 Spo0A activation inhibitor soj - Bacillus subtilis gi|467381|dbj|BAA05227.1| (D26185) regulation of Spo0J and Orf283 (probable) [Bacillus subtilis] gi|580906|emb|CAA44408.1| (X62539) unnamed protein product [Bacillus subtilis] gi|2636644|emb|CAB16134.1| (Z99124) soj [Bacillus subtilis], score 318, E-value 4.00E-86.
  
    0.442
Spo0J4
Predicted Transcriptional regulator; Best Blastp hit = gi|10176682|dbj|BAB07776.1| (AP001520) stage 0 sporulation protein J [Bacillus halodurans], score 268, E-value 5.00E-71; Belongs to the ParB family.
       0.427
GidA2
NAD/FAD-utilizing enzyme apparently involved in cell division; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
    0.422
ThdF
Predicted GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
       0.405
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.402
HisI
Phosphoribosyl-AMP cyclohydrolase; Best Blastp hit = gi|6175609|gb|AAF05095.1|AF150930_4 (AF150930) phosphoribosyl-AMP cyclohydrolase [Thermoanaerobacter ethanolicus], score 237, E-value 8.00E-62; In the C-terminal section; belongs to the PRA-PH family.
     
 0.401
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.