STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0121Similarity to known protein: 3-HYDROXYBUTYRYL-COA DEHYDRATASE (EC 4.2.1.55) (CROTONASE) - Clostridium acetobutylicum; SWISSPROT:CRT_CLOAB. (242 aa)    
Predicted Functional Partners:
Ta0476
Strong similarity to known protein: Sus scrofa L-3-hydroxyacyl-CoA dehydrogenase precursor (HAD) mRNA, nucleargene encoding mitochondrial protein, complete cds; TREMBL:AF027652_1Function: Fatty acid biosynthesis (path 2), Fatty acid metabolism, Valine, leucine and isoleucine degradation, Lysine degradation, Tryptophan metabolism, Butanoate metabolism.
 
 
 0.938
Ta0947
Similarity to known protein: beta-hydroxybutyryl-CoA dehydrogenase, NAD-dependent (EC 1.1.1.-) - Clostridium acetobutylicum; PIR:A43723Function: poly beta-hydroxybutyrate biosynthesis.
 
 
 0.938
Ta0841
Similarity to known protein: alcohol dehydrogenase (EC 1.1.1.1) - Bacillus stearothermophilus (strain DSM 2334); PIR:S47643.
  
 
 0.920
Ta0351
Similarity to known protein: sterol carrier protein x - mouse; PIR2:JU0157.
 
 0.869
Ta1456
Probable 3-ketoacyl-CoA thiolase; Similarity to known protein: probable nonspecific lipid-transfer protein - Pyrococcus horikoshii; PIR:E71113Function: Fatty acid biosynthesis (path 2), Fatty acid metabolism, Valine, leucine and isoleucine degradation, Phenylalanine metabolism.
 
 0.865
Ta0030
Probable acetyl CoA synthase; Strong similarity to known protein: P.furiosus vorA, vorB, vorD, porA, porB, porC, porD and ORFZ genes; TREMBL:PFPORVOR_4Function: Reductive carboxylate cycle (CO2 fixation).
  
 0.863
Ta0296
Strong similarity to known protein: acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [validated] - Clostridium acetobutylicum; PIR:JC4032.
  
 0.863
Ta0582
Strong similarity to known protein: acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [validated] - Clostridium acetobutylicum; PIR:JC4032.
  
 0.863
Ta0122
Xylulose kinase related protein; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Is specific for KDG.
  
    0.783
Ta0112
Strong similarity to known protein: aconitate hydratase (EC 4.2.1.3) - Legionella pneumophila; PIR:B48642.
  
 
 0.722
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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