node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ta0332 | Ta0333 | gene:9571550 | gene:9571551 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Conserved hypothetical protein; Strong similarity to unknown protein: mRNA 3'-end processing factor homolog - Archaeoglobus fulgidus; PIR:D69316. | 0.938 |
Ta0332 | Ta0355 | gene:9571550 | gene:9571573 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Spermidine synthase 2 related protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.941 |
Ta0332 | Ta0469 | gene:9571550 | gene:9571689 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.590 |
Ta0332 | Ta0568 | gene:9571550 | gene:9571788 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Similarity to known protein: phosphomannomutase (pmm) homolog - Archaeoglobus fulgidus; PIR:B69307; Belongs to the phosphohexose mutase family. | 0.556 |
Ta0332 | Ta0684 | gene:9571550 | gene:9571904 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Deoxyribose-phosphate aldolase related protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.575 |
Ta0332 | Ta0880 | gene:9571550 | gene:9572094 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Ribokinase related protein; Nucleoside kinase with broad substrate specificity. Catalyzes the phosphorylation of a variety of nucleosides to the corresponding nucleoside 5'-mono-phosphate in the presence of phosphate donors and divalent cations. Displays the most efficient activity with guanosine, followed by inosine, cytidine, and adenosine. Negligible enzymatic activity is detected with thymidine, uridine, and 2-deoxyadenosine. ATP is the most efficient phosphate donor, but can also use GTP and ITP. Shows no sugar kinase activity, since it is unable to phosphorylate ribose, fructose- [...] | 0.646 |
Ta0332 | Ta1060 | gene:9571550 | gene:9572280 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Similarity to known protein: ATRAZINE CHLOROHYDROLASE (EC 3.8.1.-) - Pseudomonas sp. (strain ADP); SWISSPROT:ATZA_PSESDFunction: FIRST STEP IN ATRAZINE DEGRADATION PATHWAY. | 0.966 |
Ta0332 | Ta1212 | gene:9571550 | gene:9572436 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Translation initiation factor aIF-2B, alpha chain related protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.708 |
Ta0332 | Ta1351 | gene:9571550 | gene:9572576 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Purine phosphoribosyltransferase related protein; Similarity to known protein: Thermus flavus askA askB and gpt genes for aspartokinase alpha-2 beta-2 andpurine phosphoribosyltransferase, complete cds; TREMBL:TFASKAB_3. | 0.537 |
Ta0332 | Ta1361 | gene:9571550 | gene:9572588 | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Probable GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.648 |
Ta0333 | Ta0332 | gene:9571551 | gene:9571550 | Conserved hypothetical protein; Strong similarity to unknown protein: mRNA 3'-end processing factor homolog - Archaeoglobus fulgidus; PIR:D69316. | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.938 |
Ta0355 | Ta0332 | gene:9571573 | gene:9571550 | Spermidine synthase 2 related protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.941 |
Ta0355 | Ta1060 | gene:9571573 | gene:9572280 | Spermidine synthase 2 related protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | Similarity to known protein: ATRAZINE CHLOROHYDROLASE (EC 3.8.1.-) - Pseudomonas sp. (strain ADP); SWISSPROT:ATZA_PSESDFunction: FIRST STEP IN ATRAZINE DEGRADATION PATHWAY. | 0.920 |
Ta0355 | Ta1212 | gene:9571573 | gene:9572436 | Spermidine synthase 2 related protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | Translation initiation factor aIF-2B, alpha chain related protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.566 |
Ta0469 | Ta0332 | gene:9571689 | gene:9571550 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Purine-nucleoside phosphorylase related protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.590 |
Ta0469 | Ta0568 | gene:9571689 | gene:9571788 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Similarity to known protein: phosphomannomutase (pmm) homolog - Archaeoglobus fulgidus; PIR:B69307; Belongs to the phosphohexose mutase family. | 0.493 |
Ta0469 | Ta0880 | gene:9571689 | gene:9572094 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Ribokinase related protein; Nucleoside kinase with broad substrate specificity. Catalyzes the phosphorylation of a variety of nucleosides to the corresponding nucleoside 5'-mono-phosphate in the presence of phosphate donors and divalent cations. Displays the most efficient activity with guanosine, followed by inosine, cytidine, and adenosine. Negligible enzymatic activity is detected with thymidine, uridine, and 2-deoxyadenosine. ATP is the most efficient phosphate donor, but can also use GTP and ITP. Shows no sugar kinase activity, since it is unable to phosphorylate ribose, fructose- [...] | 0.760 |
Ta0469 | Ta1060 | gene:9571689 | gene:9572280 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Similarity to known protein: ATRAZINE CHLOROHYDROLASE (EC 3.8.1.-) - Pseudomonas sp. (strain ADP); SWISSPROT:ATZA_PSESDFunction: FIRST STEP IN ATRAZINE DEGRADATION PATHWAY. | 0.464 |
Ta0469 | Ta1212 | gene:9571689 | gene:9572436 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Translation initiation factor aIF-2B, alpha chain related protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.503 |
Ta0469 | Ta1361 | gene:9571689 | gene:9572588 | Probable adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Probable GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.401 |