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uppS protein (Thermoplasma acidophilum) - STRING interaction network
"uppS" - Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) in Thermoplasma acidophilum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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uppSTritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids (258 aa)    
Predicted Functional Partners:
Ta1313
Geranylgeranyl pyrophosphate synthase related protein; Similarity to known protein- probable idsA2 protein - Mycobacterium tuberculosis (strain H37RV); PIR-G70935; Belongs to the FPP/GGPP synthase family (354 aa)
 
  0.961
Ta0520
Similarity to unknown protein- conserved hypothetical protein AF0706 - Archaeoglobus fulgidus; PIR-B69338 (236 aa)
         
  0.903
Ta0436
Similarity to known protein- BIFUNCTIONAL SHORT CHAIN ISOPRENYL DIPHOSPHATE SYNTHASE [INCLUDES-FARNESYL PYROPHOSPHATE SYNTHETASE (EC 2.5.1.1) (FPP SYNTHETASE)(DIMETHYLALLYLTRANSFERASE); GERANYLTRANSTRANSFERASE (EC 2.5.1.10)] - Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133); SWISSPROT-IDSA_METTM (322 aa)
 
 
  0.868
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA (440 aa)
              0.856
Ta0364
Similarity to known protein- A.thaliana mRNA for aspartate kinase; TREMBL-ATAKLYS1_1 (272 aa)
   
 
  0.818
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (348 aa)
   
   
  0.814
ubiA
4-hydroxybenzoate octaprenyl transferase related protein; UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin (286 aa)
   
   
  0.804
Ta0079
Similarity to known protein- dihydropteroate synthase (EC 2.5.1.15) - Neisseria meningitidis (strain BT054); PIR-S65837ORF_prediction- This ORF has an N-terminal extension compared to related dihydropteroate synthase or about 80 amino acids. Neither codon usage nor frequency of rare codons suggest a later start of the ORF (347 aa)
   
   
  0.800
Ta1305
Mevalonate-3-kinase; Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative Thermoplasma-type mevalonate pathway, which passes through mevalonate 3-phosphate rather than mevalonate 5-phosphate (318 aa)
         
  0.787
Ta0461
Uncharacterized protein (384 aa)
         
  0.781
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum, Thermoplasma acidophilum DSM 1728, Thermoplasma acidophilum DSM1728
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