STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Ta0815Tricorn protease interacting factor F3; Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids; Belongs to the peptidase M1 family. (780 aa)    
Predicted Functional Partners:
Ta0446
Translation elongation factor aEF-2 related protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translati [...]
  
 
 0.666
Ta0813
Conserved hypothetical protein; Strong similarity to unknown protein: tldD-related protein PH0848 - Pyrococcus horikoshii; PIR:D71135.
     
 0.608
Ta0814
Similarity to unknown protein: hypothetical protein PH0849 - Pyrococcus horikoshii; PIR:E71135.
     
 0.608
Ta0811
Similarity to known protein: glycine hydroxymethyltransferase (EC 2.1.2.1) - Methanobacterium thermoautotrophicum (strain Marburg); PIR:S62190Function: involved in glycine, serine and threonine metabolism, also involved in vitamin B6 metabolism.
   
 
 0.576
Ta1419
Conserved hypothetical protein; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency; Belongs to the PGI/PMI family.
  
 
 0.480
Ta0812
Similarity to unknown protein: hypothetical protein MJ1404 - Methanococcus jannaschii; PIR:C64475.
  
  
 0.469
Ta0882
Enolase related protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.435
Ta0162
Similarity to known protein: NADH oxidase (EC 1.-.-.-) - Thermoanaerobacter brockii; PIR:S35706.
  
 
 0.432
Ta0465
Similarity to known protein: intracellular proteinase I (EC 3.4.-.-) - Pyrococcus furiosus; PIR:JC6003.
  
 
 0.430
Ta0830
Proline iminopeptidase; Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N- terminus. Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome) yielding free amino acids.
 
 
 0.424
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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