STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0937prolyl-tRNA synthetase related protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (462 aa)    
Predicted Functional Partners:
Ta1269
Probable 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
 0.987
Ta1297
Strong similarity to known protein: ribosomal protein L21.eR [validated] - Haloarcula marismortui; PIR1:R5HS31; Belongs to the eukaryotic ribosomal protein eL21 family.
   
 0.982
Ta1252
Probable 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 0.977
Ta0054
Similarity to known protein: 60S RIBOSOMAL PROTEIN L31 - Nicotiana glutinosa (Tobacco); SWISSPROT:RL31_NICGU; Belongs to the eukaryotic ribosomal protein eL31 family.
   
 0.976
Ta1266
Probable 50S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 0.976
Ta1114
Probable 50S ribosomal protein L24E; Binds to the 23S rRNA.
  
 0.975
Ta1254
Similarity to known protein: 50S RIBOSOMAL PROTEIN L32E - Sulfolobus acidocaldarius; SWISSPROT:RL32_SULAC; Belongs to the eukaryotic ribosomal protein eL32 family.
  
 0.975
Ta1255
Probable 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 0.975
Ta0433
Probable 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 0.973
Ta0359
Acidic ribosomal protein P0 related protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.969
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.