STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0945Transcription initiation factor IIB related protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (307 aa)    
Predicted Functional Partners:
Ta0199
Probable TATA-box binding protein (TFIID homolog); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
 
 0.951
Ta1020
Similarity to known protein: TRANSCRIPTION INITIATION FACTOR IIB HOMOLOG (TFIIB) - Pyrococcus furiosus; SWISSPROT:TF2B_PYRFU.
 
  
 
0.924
Ta0940
Transcription initiation factor IIB related protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
 
  
 
0.905
Ta0389
DNA-DIRECTED RNA POLYMERASE CHAIN H related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
    
 0.865
Ta1030
DNA-dependent RNA polymerase, subunit D related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
   
 0.864
Ta1016
Similarity to known protein: Saccharomyces cerevisiae DNA helicase (RAD25) gene, complete cds; TREMBL:SCRAD25A_1.
    
 0.862
Ta1160
Probable DNA-directed RNA polymerase, chain K (rpok); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
    
 0.861
Ta0390
Probable DNA-directed RNA polymerase chain B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.859
Ta0431
DNA-directed RNA polymerase, chain N related protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
   
 0.859
Ta1006
Probable transcription-associated protein TFIIS; Strong similarity to known protein: DNA-DIRECTED RNA POLYMERASE SUBUNIT M (EC 2.7.7.6) - Thermococcus celer; SWISSPROT:RPOM_THECE; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
   
 0.853
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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