STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0972L-asparaginase related protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (409 aa)    
Predicted Functional Partners:
Ta0971
Glu-tRNA amidotransferase, subunit B related protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
 0.999
Ta0258
Probable fumarase; Strong similarity to known protein: Bacillus subtilis 42.7kB DNA fragment from yvsA to yvqA; TREMBLNEW:BS43KBDNA_39.
 
  
 0.871
Ta0506
Thiazole biosynthesis protein Thi I related protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.836
Ta0315
Similarity to known protein: Mus musculus asparagine synthetase mRNA, complete cds; TREMBL:MM38940_1.
 
  
 0.689
Ta1361
Probable GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.637
Ta0973
Similarity to unknown protein: hypothetical protein aq_926 - Aquifex aeolicus; PIR:C70380.
       0.603
Ta0791
Probable carbamoyl-phosphate synthase, large subunit; Strong similarity to known protein: carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus; PIR:I40169.
   
 0.583
Ta0944
GMP synthase related protein; Catalyzes the synthesis of GMP from XMP.
  
 
  0.574
Ta0044
Probable CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
  0.565
Ta0969
Probable NADH dehydrogenase, chain B; Strong similarity to known protein: NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain NQO6 - Thermus aquaticus thermophilus; PIR:T11899; Belongs to the complex I 20 kDa subunit family.
 
    0.559
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.