STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1119Strong similarity to unknown protein: hypothetical protein PAB2029 - Pyrococcus abyssi (strain Orsay); PIR:H75166. (314 aa)    
Predicted Functional Partners:
Ta1442
Hypothetical protein.
  
 
 0.833
Ta0852
Similarity to unknown protein: conserved hypothetical protein - Thermotoga maritima (strain MSB8); PIR:G72340.
 
  
 0.824
Ta0506
Thiazole biosynthesis protein Thi I related protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.760
Ta0932
tRNA-pseudouridine synthase I related protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
 
 
 0.747
Ta1311
Probable Histone and other Protein Acetyltransferase (yeast HPA1); Strong similarity to known protein: histone acetyltransferase (EC 2.3.1.48), RNA polymerase II-associated [validated] - yeast (Saccharomyces cerevisiae); PIR2:S61980.
   
 
 0.720
Ta0214
Conserved hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
 
 0.690
Ta0844
Similarity to known protein: molybdopterin biosynthesis protein moeB - Escherichia coli; PIR:B32352.
  
 
 0.670
Ta1365
Conserved hypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
  
 0.656
Ta1244
Dyskerin (nucleolar protein Nap57) related protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.653
Ta0256
Hypothetical protein.
 
   
 0.627
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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