STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1211tryptophanyl-tRNA synthetase related protein; Similarity to known protein: H.sapiens mRNA for IFP53; TREMBL:HSIFP53_1; Belongs to the class-I aminoacyl-tRNA synthetase family. (426 aa)    
Predicted Functional Partners:
Ta0468
Probable seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
 
 0.866
Ta0460
Endonuclease V related protein; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity); In the N-terminal section; belongs to the MGMT family.
       0.813
Ta1493
Queuine tRNA-ribosyltransferase related protein; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.797
Ta0551
Similarity to known protein: PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN CYTOPLASMIC (EC 6.1.1.20)(PHENYLALANINE--TRNA LIGASE ALPHA CHAIN) (PHERS) - Candida albicans (Yeast); SWISSPROT:SYFA_CANAL.
  
  
 0.792
Ta0281
Similarity to known protein: arginine--tRNA ligase (EC 6.1.1.19) - Corynebacterium glutamicum; PIR1:A49936; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.778
Ta0639
Similarity to known protein: phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain, cytosolic [validated] - yeast (Saccharomyces cerevisiae); PIR:YFBYAC; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
  
 0.772
Ta0777
Similarity to known protein: leucyl-tRNA synthetase (leuS) homolog - Archaeoglobus fulgidus; PIR:F69552; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.772
Ta0879
isoleucyl-tRNA synthetase related protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
 0.764
Ta0324
O-sialoglycoprotein endopeptidase related protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr pro [...]
 
  
 0.755
Ta0330
threonine--tRNA ligase related protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
  
 0.724
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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