STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1214Similarity to known protein: Canarypox virus gene for thymidine kinase and 8 ORFs, partial and completecds; TREMBL:D86731_5. (186 aa)    
Predicted Functional Partners:
Ta0081
Conserved hypothetical protein; Similarity to unknown protein: thymidylate kinase (tmk) homolog - Archaeoglobus fulgidus; PIR:E69257.
  
 
 0.957
Ta0312
Probable dCMP deaminase; Strong similarity to known protein: Yeast (S.cerevisiae) dCMP deaminase gene (DCD1), complete cds; TREMBL:SCDCD1_1.
  
 
 0.944
Ta0044
Probable CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.761
Ta1059
Translation initiation factor eIF-5a related protein; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
  
 0.695
Ta1213
Purine-cytosine permease related protein; Similarity to known protein.
       0.662
Ta1475
Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase class-2 family.
  
  
 0.565
Ta0114
N-methyl-transferase related protein; Similarity to known protein: S.alboniger napH, pur7, pur10, pur6, pur4, pur5 and pur3 genes; TREMBL:SAPURCLUS_7.
  
  
 0.548
Ta0684
Deoxyribose-phosphate aldolase related protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.535
Ta1055
Probable DNA gyrase, subunit B (gyrB); Strong similarity to known protein: DNA topoisomerase chain B homolog - Haloferax sp; PIR:A39135.
  
  
 0.526
Ta0313
Triosephosphate isomerase related protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.521
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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