STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta1493Queuine tRNA-ribosyltransferase related protein; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (632 aa)    
Predicted Functional Partners:
Ta1492
Strong similarity to known protein: RNase L inhibitor (clone 8) - human; PIR:S63672.
  
    0.947
Ta0924
Similarity to unknown protein: hypothetical protein PH0135 - Pyrococcus horikoshii; PIR:E71234.
 
  
 0.946
Ta1491
Strong similarity to unknown protein: hypothetical 17.7K protein - Thermoplasma acidophilum; PIR:T43256.
       0.936
Ta0852
Similarity to unknown protein: conserved hypothetical protein - Thermotoga maritima (strain MSB8); PIR:G72340.
  
  
 0.924
Ta1244
Dyskerin (nucleolar protein Nap57) related protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.869
Ta0948
Similarity to unknown protein: conserved hypothetical protein MTH729 - Methanobacterium thermoautotrophicum (strain Delta H); PIR:D69197. Relation: ethylene-responsive transcriptional coactivator related protein conserved hypothetical protein TREMBLNEW:AF096246_1.
 
     0.865
Ta1133
Weak similarity to unknown protein.
 
    0.854
Ta1132
Similarity to unknown protein: hypothetical protein PH0059 - Pyrococcus horikoshii; PIR:H71224.
 
    0.852
Ta0017
Hypothetical membrane protein; Weak similarity to known protein. Relation: weak similarity to PIR2:S27868.
  
    0.851
Ta1447
Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.851
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.