STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0216Conserved hypothetical protein; Similarity to unknown protein: probable methyltransferase - Pyrococcus horikoshii; PIR:F71131. (535 aa)    
Predicted Functional Partners:
Ta0546
Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
    0.787
Ta0215
Conserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.637
Ta0491
P-methyltransferase related protein; Similarity to known protein: Streptomyces hygroscopicus genes for P-methylase and bialaphosbiosynthesis-related unknown product, complete cds; TREMBL:SHBCPD_2.
  
     0.619
Ta0350
Similarity to unknown protein: hypothetical protein APE1894 - Aeropyrum pernix (strain K1); PIR:F72576.
  
     0.558
Ta0214
Conserved hypothetical protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
     0.554
Ta0451
Cell division control protein 6 related protein; Involved in regulation of DNA replication (By similarity). Has no effect on MCM helicase activity, either stimulatory or inhibitory. Does not bind DNA.
 
     0.515
Ta0118
Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity).
       0.507
Ta1187
Similarity to unknown protein: hypothetical protein TM1336 - Thermotoga maritima (strain MSB8); PIR:H72265.
 
     0.504
Ta0217
Strong similarity to unknown protein: hypothetical protein APE0252 - Aeropyrum pernix (strain K1); PIR:C72783.
       0.456
Ta0218
Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.441
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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